ArticleJournal of assisted reproduction and genetics2019
Counseling young women with early breast cancer on fertility preservation.
Article in Journal of assisted reproduction and genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 51 citations in OpenAlex.
- Breaking the Silence: Barriers to Fertility Preservation Among Young Breast Cancer Patients in Ghana - a multicenter study.Research square · 2025Article
- Quality-of-Life Assessment in Patients Undergoing Mastectomy and Breast Reconstruction for Moderate-Penetrance Gene-Related Breast Cancer.Journal of clinical medicine · 2025Article
- Outcomes of female fertility preservation with cryopreservation of oocytes or embryos in the Netherlands: a population-based study.Human reproduction (Oxford, England) · 2024Observational
- Perceptions and experiences of fertility preservation in female patients with cancer in Greece.BMC women's health · 2024Article
- Knowledge and intentions to use fertility preservation among urban Chinese cancer patients: A study from Hong Kong.PloS one · 2024Article
- Prognostic effect of subsequent childbirth after the diagnosis of breast cancer using propensity score matching analysis.Breast cancer (Tokyo, Japan) · 2023Article
- Impact of Breast Cancer and Germline BRCA Pathogenic Variants on Fertility Preservation in Young Women.Life (Basel, Switzerland) · 2023Article
- Psychological issues in breast cancer survivors confronted with motherhood: Literature review and a call to action.Frontiers in psychology · 2023Review
- Prevalent versus incident breast cancers: benefits of clinical and radiological monitoring in women with pathogenic BRCA1/2 variants.European journal of human genetics : EJHG · 2022Article
- Review
- Update on fertility preservation for younger women with breast cancer.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020Review
- Preserving fertility in young women undergoing chemotherapy for early breast cancer; the Maastricht experience.Breast cancer research and treatment · 2020Article
- Breast cancer: an update on treatment-related infertility.Journal of cancer research and clinical oncology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWomen with early-stage breast cancer may still have a future child wish, while chemotherapy may impair fertility. To pursue on fertility preservation shortly after breast cancer diagnosis is complex. This review holds a critical reflection on all topics that need to be counseled to give them the opportunity to make a well-informed decision before starting any oncological treatment.
methodsA comprehensive literature review was performed on papers published in English language on breast cancer in young women, risk of chemotherapy-induced infertility, fertility preservation techniques, impact of possible mutation carriership, and future pregnancy outcome.
resultsBelow 40 years of age, the risk of permanent chemotherapy-induced ovarian function failure is approximately 20%, where taxanes do not significantly add to this risk. Overall, 23% of reported women who performed fertility preservation by cryopreserving oocytes or embryos returned for embryo transfer. Of these, 40% gave live birth. Both fertility preservation in women diagnosed with breast cancer and pregnancy after treatment seem safe with respect to breast cancer survival. Women who have a genetic predisposition for breast cancer like BRCA gene mutation should also be informed about the possibility of pre-implantation genetic diagnosis.
conclusionsWomen with an early stage of breast cancer and a possible future child wish should be referred to an expertise center in breast cancer, fertility preservation, and genetics in this complex decision-making process, shortly after diagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.