ArticleJapanese journal of ophthalmology2020
Association between axial length and in vivo human crystalline lens biometry during accommodation: a swept-source optical coherence tomography study.
Article in Japanese journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The trial behind it
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Who cites it
14 citing papers in PubMed.
- Crystalline Lens Shape During Accommodation in Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Crystalline lens geometry from a clinical OCT-based biometer in pre-cataract surgery patients.Research square · 2026Article
- In vivo characterization of morphologic changes in the lens during accommodation as a function of age by use of OCT with swept-source technology.Japanese journal of ophthalmology · 2025Observational
- Hyperopic Eyes Are Structurally More Dynamic Than Myopic Eyes During Accommodation: An In Vivo Investigation.Investigative ophthalmology & visual science · 2025Article
- Dynamic refraction and anterior segment OCT biometry during accommodation.Biomedical optics express · 2024Article
- Analysis of the relationship between lens morphology and aberrations in patients with myopia: a cross-sectional study.International ophthalmology · 2023Article
- Article
- Detection of Anterior Hyaloid Membrane Detachment Using Deep-Range Anterior Segment Optical Coherence Tomography.Journal of clinical medicine · 2022Article
- Effects of 0.01% Atropine Instillation Assessed Using Swept-Source Anterior Segment Optical Coherence Tomography.Journal of clinical medicine · 2021Article
- Quantitative analysis of internal components of the human crystalline lens during accommodation in adults.Scientific reports · 2021Article
- Subtle changes of the crystalline lens after cycloplegia: a retrospective study.BMC ophthalmology · 2021Article
- Age-dependent changes in visual sensitivity induced by moving fixation points in adduction and abduction using imo perimetry.Scientific reports · 2020Article
- The Structure of the Lens and Its Associations with the Visual Quality.BMJ open ophthalmology · 2020Review
- Anterior Segment Biometry During Accommodation and Effects of Cycloplegics by Swept-Source Optical Coherence Tomography.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
purposeTo evaluate the association between axial length and crystalline lens biometry with and without accommodation using the CASIA2 swept-source (SS) optical coherence tomography (OCT) system on the anterior segment. STUDY
designIntervention study.
methodsIndividuals aged 20 to 39 years were enrolled for SS-OCT imaging at 2 separate visits within 1 week. Each eye was imaged under accommodation stimuli with different amplitudes (0 D, -1 D, -3 D, -5 D, and -7 D). The anterior and posterior lens curvature radii and lens thicknesses were measured. The participants were divided into 4 groups according to axial length.
resultsForty-eight participants (96 eyes) were initially enrolled. All 96 eyes were included in the analyses, as they met the eligibility criteria and each had proper OCT images. The mean participant age was 25.9 ± 4.3 years, and the mean spherical error was -3.5 ± 2.5 D. The mean axial length was 25.1 ± 1.2 mm. Multivariate analysis revealed that the anterior curvature radius became flatter and the lens thickness became thicker as the axial length increased (all P < .01). Furthermore, axial length independently contributed to the shape of the lens after adjusting for the effects of age and accommodation stimuli.
conclusionAxial length was associated with lens shape after adjusting for age and accommodation stimuli. These measurements can provide a glimpse of dynamic lens biometry changes, which may help us better understand the role of lenses in various physiologic changes, including accommodation and myopia.
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