Evidence map›Paper›PMID 31760063›Full record

ArticleToxicology letters2020

Disposition and metabolism of N-butylbenzenesulfonamide in Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans.

Suramya Waidyanatha, Sherry R Black, Purvi R Patel, Cynthia V Rider, Scott L Watson, Rodney W Snyder, Timothy R Fennell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Immunotoxicity of N-butylbenzenesulfonamide: impacts on immune function in adult mice and developmentally exposed rats.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Suramya WaidyanathaDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA. Electronic address: waidyanathas@niehs.nih.gov.
Sherry R BlackRTI International, Discovery Sciences, Research Triangle Park, NC, USA.
Purvi R PatelRTI International, Discovery Sciences, Research Triangle Park, NC, USA.
Cynthia V RiderDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Scott L WatsonRTI International, Discovery Sciences, Research Triangle Park, NC, USA.
Rodney W SnyderRTI International, Discovery Sciences, Research Triangle Park, NC, USA.
Timothy R FennellRTI International, Discovery Sciences, Research Triangle Park, NC, USA.
RTI International · USNational Institute of Environmental Health Sciences · US

Funding

Integrated Health Assessments for the National Toxicology ProgramZIAES103317 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ROONEY, ANDREW · 2016 to 2019
$24.4M
Toxicological Assessments for the Division of the National Toxicology ProgramZICES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2020 to 2021
$18.5M
Intramural NIH HHS Z99 ES999999NIEHS NIH HHS HHSN273201400027C
6 · The paper itself

Abstract

N-Butylbenzenesulfonamide (NBBS) is a plasticizer detected in the environment suggesting potential human exposure. These studies investigated the in vitro hepatic clearance and disposition of [

Indexed as

Administration, IntravenousAnimalsBenzenesulfonamidesBileCells, CulturedFecesFemaleHepatocytesHumansIntubation, GastrointestinalMaleMiceMice, Inbred StrainsPlasticizersRatsRats, Sprague-DawleyBenzenesulfonamidesN-butylbenzenesulfonamidePlasticizersSulfonamidesAbsorptionDistributionExcretionMetabolismN-butylbenzenesulfonamidePlasticizer

Identifiers

PMID31760063
PMCPMC7028346
OpenAlexW2990775847

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.