Evidence map›Paper›PMID 31759961›Full record

ArticleChest2020

Screening Heroin Smokers Attending Community Drug Clinics for Change in Lung Function: A Cohort Study.

Rebecca Nightingale, Kevin Mortimer, Emanuele Giorgi, Paul P Walker, Marie Stolbrink, Tara Byrne, Kerry Marwood, Sally Morrison-Griffiths, Susan Renwick, Jamie Rylance and 1 more

Abstract read
In one paragraph

Article in Chest, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Changes in lung function in adolescents with substance use disorders: an exploratory study.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Observational
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Rebecca NightingaleLiverpool School of Tropical Medicine, Liverpool, England.
Kevin MortimerLiverpool School of Tropical Medicine, Liverpool, England.
Emanuele GiorgiCHICAS, Lancaster University, England.
Paul P WalkerUniversity Hospital Aintree, Liverpool, England.
Marie StolbrinkUniversity Hospital Aintree, Liverpool, England.
Tara ByrneAddaction, Liverpool, England.
Kerry MarwoodAddaction, Liverpool, England.
Sally Morrison-GriffithsAddaction, Liverpool, England.
Susan RenwickLiverpool Clinical Commissioning Group, Liverpool, England.
Jamie RylanceLiverpool School of Tropical Medicine, Liverpool, England; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi. Electronic address: Jamie.rylance@lstmed.ac.uk.
Hassan BurhanRoyal Liverpool and Broadgreen University Hospitals, Liverpool, England.

Funding

Medical Research Council
6 · The paper itself

Abstract

backgroundHeroin smokers have high rates of COPD, respiratory morbidity, hospital admission, and mortality. We assessed the natural history of symptoms and lung function in this population over time.

methodsA cohort of heroin smokers with COPD was followed for 18 to 24 months. At baseline and follow-up, respiratory symptoms were measured by the Medical Research Council Dyspnea Scale (MRC) and the COPD Assessment Tool (CAT), and postbronchodilator spirometry was performed. Frequency of health-care-seeking episodes was extracted from routine health records. Parametric, nonparametric, and linear regression models were used to analyze the change in symptoms and lung function over time.

resultsOf 372 participants originally recruited, 161 were assessed at follow-up (mean age, 51.0 ± 5.3 years; 74 women [46%]) and 106 participants completed postbronchodilator spirometry. All participants were current or previous heroin smokers, and 122 (75.8%) had smoked crack. Symptoms increased over time (MRC score increased by 0.48 points per year, P < .001; CAT score increased by 1.60 points per year, P < .001). FEV

conclusionsHeroin smokers experience a high and increasing burden of chronic respiratory symptoms and a decline in FEV

Indexed as

Bronchodilator AgentsCigarette SmokingCocaine SmokingCohort StudiesDisease ProgressionEmergency Service, HospitalFemaleForced Expiratory VolumeHeroin DependenceHospitalizationHumansLongitudinal StudiesLungMaleMarijuana SmokingMass ScreeningBronchodilator AgentsCOPDheroinopiatespirometry

Identifiers

PMID31759961
PMCPMC7078587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.