ReviewDevelopmental and comparative immunology2020
Biomphalaria glabrata immunity: Post-genome advances.
Review in Developmental and comparative immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed.
- Development of long-term oyster explant cultures enable sustained tissue-specific activity and reveal novel cellular behaviours.Biochemistry and biophysics reports · 2026Article
- Review
- Dynamic Effects ofBiology · 2026Article
- Article
- Limited impact of schistosome infection on Biomphalaria glabrata snail microbiomes.Parasites & vectors · 2026Article
- Snail 3G: genomics, genetics, and gene-editing ofFrontiers in genetics · 2026Review
- Introduction of epigenetic variation contribute to resistance against the human parasite Schistosoma mansoni.Epigenetics & chromatin · 2025Article
- Lipids from a snail host regulate the multicellular behavior of a predator of parasitic schistosomes.iScience · 2024Article
- Susceptibility of BS90 Biomphalaria glabrata snails to infection by SmLE Schistosoma mansoni segregates as a dominant allele in a cluster of polymorphic genes for single-pass transmembrane proteins.PLoS neglected tropical diseases · 2024Article
- Article
- Article
- Host lipids regulate multicellular behavior of a predator of a human pathogen.bioRxiv : the preprint server for biology · 2024Article
- Assessing the microbiota of the snail intermediate host of trematodes, Galba truncatula.Parasites & vectors · 2024Article
- SlugAtlas, a histological and 3D online resource of the land slugs Deroceras laeve and Ambigolimax valentianus.PloS one · 2024Article
- Exploring the immune interactions between Oncomelania hupensis and Schistosoma japonicum, with a cross-comparison of immunological research progress in other intermediate host snails.Parasites & vectors · 2023Review
- The genome and transcriptome of the snailbioRxiv : the preprint server for biology · 2023Article
- Status Quo and Future Perspectives of Molecular and Genomic Studies on the GenusInternational journal of molecular sciences · 2023Review
- Nuclear genome of Bulinus truncatus, an intermediate host of the carcinogenic human blood fluke Schistosoma haematobium.Nature communications · 2022Article
- Single-cell RNA-seq profiling of individual Biomphalaria glabrata immune cells with a focus on immunologically relevant transcripts.Immunogenetics · 2022Article
- Schiff bases complexed with iron and their relation with the life cycle and infection byFrontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The freshwater snail, Biomphalaria glabrata, is an important intermediate host in the life cycle for the human parasite Schistosoma mansoni, the causative agent of schistosomiasis. Current treatment and prevention strategies have not led to a significant decrease in disease transmission. However, the genome of B. glabrata was recently sequenced to provide additional resources to further our understanding of snail biology. This review presents an overview of recently published, post-genome studies related to the topic of snail immunity. Many of these reports expand on findings originated from the genome characterization. These novel studies include a complementary gene linkage map, analysis of the genome of the B. glabrata embryonic (Bge) cell line, as well as transcriptomic and proteomic studies looking at snail-parasite interactions and innate immune memory responses towards schistosomes. Also included are biochemical investigations on snail pheromones, neuropeptides, and attractants, as well as studies investigating the frontiers of molluscan epigenetics and cell signaling were also included. Findings support the current hypotheses on snail-parasite strain compatibility, and that snail host resistance to schistosome infection is dependent not only on genetics and expression, but on the ability to form multimeric molecular complexes in a timely and tissue-specific manner. The relevance of cell immunity is reinforced, while the importance of humoral factors, especially for secondary infections, is supported. Overall, these studies reflect an improved understanding on the diversity, specificity, and complexity of molluscan immune systems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.