ArticleJournal of affective disorders2020
Treating depressive disorders with the Unified Protocol: A preliminary randomized evaluation.
Article in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Preliminary Findings on the Unified Protocol for Transdiagnostic Treatment: A Pilot Trial on Its Effectiveness on Anxiety and Depressive Symptoms for Turkish Adults.Journal of clinical psychology · 2026Trial
- Feasibility, Acceptability, and Preliminary Efficacy of a Smartphone App-Led Cognitive Behavioral Therapy for Depression Under Therapist Supervision: Open Trial.JMIR mental health · 2024Trial
- Efficacy of the unified protocol for transdiagnostic cognitive-behavioral treatment for depressive and anxiety disorders: a randomized controlled trial.Psychological medicine · 2023Trial
- A pilot randomized effectiveness trial of the unified protocol in trauma-exposed veterans.Depression and anxiety · 2022Trial
- Does the unified protocol really change neuroticism? Results from a randomized trial.Psychological medicine · 2021Trial
- Transdiagnostic treatment of emotional disorders in people with multiple sclerosis: randomized controlled trial.BMC psychology · 2020Trial
- Co-occurring mental and substance use disorders in Australia 2020-2022: Prevalence, patterns, conditional probabilities and correlates in the general population.The Australian and New Zealand journal of psychiatry · 2025Article
- Patterns of Skills Review in Smartphone Cognitive Behavioral Therapy for Depression: Observational Study of Intervention Content Use.JMIR mental health · 2025Observational
- Depression, anxiety, and personal recovery outcomes after group vs individual transdiagnostic therapy: a brief report.Scientific reports · 2024Article
- Article
- Internet- and mobile-based aftercare and relapse prevention interventions for anxiety and depressive disorders: a systematic review.Frontiers in psychology · 2024Review
- Application of unified protocol as a transdiagnostic treatment for emotional disorders during COVID-19: An internet-delivered randomized controlled trial.World journal of clinical cases · 2022Article
- App-enhanced transdiagnostic CBT for adolescents with mood or psychotic spectrum disorders.Journal of affective disorders · 2022Article
- An Ecological Momentary Intervention Study of Emotional Responses to Smartphone-Prompted CBT Skills Practice and the Relationship to Clinical Outcomes.Behavior therapy · 2022Article
- Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022Article
- Brief Transdiagnostic Intervention for Parents With Emotional Disorder Symptoms During the COVID-19 Pandemic: A Case Example.Cognitive and behavioral practice · 2021Article
- Treatment for Anxiety and Comorbid Depressive Disorders: Transdiagnostic Cognitive-Behavioral Strategies.Psychiatric annals · 2021Article
- Using Fear and Anxiety Related to COVID-19 to Predict Cyberchondria: Cross-sectional Survey Study.Journal of medical Internet research · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectivesThis study aims to examine the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) for individuals diagnosed with a depressive disorder.
methodParticipants included 44 adults who met criteria for major depressive disorder, persistent depressive disorder, or another specified depressive disorder according to the Anxiety Disorder Interview Schedule (ADIS). These individuals represent a subset of patients from a larger clinical trial comparing the UP to single-disorder protocols (SDPs) for discrete anxiety disorders and a waitlist control (WLC) condition (Barlow et al., 2017); inclusion criteria for the parent study required participants to have a principal anxiety disorder.
resultsSignificant reductions in depressive symptoms were observed within the UP condition across clinician-rated and self-report measures of depression from baseline to post-treatment, as well as to the 12-month follow-up assessment. Compared to the WLC group, individuals in the UP condition demonstrated significantly lower levels on our continuous, clinician-rated measure of depressive symptoms at post-treatment. There were no differences between the UP and SDP conditions on depressive symptoms at post-treatment or at the 12-month follow-up timepoint.
conclusionsIn this exploratory set of analyses, the UP evidenced efficacy for reduction of depressive symptoms, adding to the growing support for its utility in treating depression.
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