ReviewNeuroimaging clinics of North America2020
Widespread Morphometric Abnormalities in Major Depression: Neuroplasticity and Potential for Biomarker Development.
Review in Neuroimaging clinics of North America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Diagnostic Constructs of Major Depression in DSM-5: Current Critiques and Future Directions.Advances in experimental medicine and biology · 2026Review
- Neuroanatomical dimensions in major depression linked to cognition, adverse life events, self-harm, metabolomics and genetics.Communications medicine · 2025Article
- Food insecurity and subjective cognitive complaints among adults aged ≥ 65 years from low- and middle-income countries.European journal of nutrition · 2023Article
- AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale.BMC psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Major depression is common and debilitating. Identifying neurobiological subtypes that comprise the disorder and predict clinical outcome are key challenges. Genetic and environmental factors leading to major depression are expressed in neural structure and function. Volumetric decreases in gray matter have been demonstrated in corticolimbic circuits involved in emotion regulation. MR imaging observable abnormalities reflect cytoarchitectonic alterations within a local neuroendocrine milieu with systemic effects. Multivariate pattern analysis offers the potential to identify the neurobiological subtypes and predictors of clinical outcome. It is essential to characterize disease heterogeneity by incorporating data-driven inductive and symptom-based deductive approaches in an iterative process.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.