Evidence map›Paper›PMID 31759570›Full record

ReviewNeuroimaging clinics of North America2020

Imaging-Based Subtyping for Psychiatric Syndromes.

Elena I Ivleva, Halide B Turkozer, John A Sweeney

Abstract readReview
In one paragraph

Review in Neuroimaging clinics of North America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. BIOMARKERS AND NEUROBEHAVIORAL DIAGNOSIS.Biomarkers in neuropsychiatry · 2021
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elena I IvlevaDepartment of Psychiatry, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, NC5, Dallas, TX 75390, USA. Electronic address: elena.ivleva@utsouthwestern.edu.
Halide B TurkozerDepartment of Psychiatry, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, NC5, Dallas, TX 75390, USA.
John A SweeneyDepartment of Psychiatry, University of Cincinnati, 2600 Clifton Avenue, Cincinnati, OH 45221, USA.

Funding

Bipolar & Schizophrenia Consortium for Parsing Intermediate PhenotypesR01MH077851 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI TAMMINGA, CAROL A · 2007 to 2019
$7.8M
Bipolar & Schizophrenia Consortium for Parsing Intermediate PhenotypesR01MH077862 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI SWEENEY, JOHN A · 2007 to 2010
$3.1M
Psychosis and Affective Research Domains and Intermediate Phenotypes (PARDIP)R01MH096913 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI TAMMINGA, CAROL A · 2013 to 2015
$950k
Neural Network Biomarkers for Relational Memory and Psychosis in SchizophreniaK23MH102656 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI IVLEVA, ELENA IVANOVNA · 2014 to 2017
$679k
NIMH NIH HHS K23 MH102656NIMH NIH HHS R01 MH077851NIMH NIH HHS R01 MH077862NIMH NIH HHS R01 MH096913
6 · The paper itself

Abstract

Despite considerable research evidence demonstrating significant neurobiological alterations in psychiatric disorders, incorporating neuroimaging approaches into clinical practice remains challenging. There is an urgent need for biologically validated psychiatric disease constructs that can inform diagnostic algorithms and targeted treatment development. In this article, we present a conceptual review of the most robust and impactful findings from studies that use neuroimaging methods in efforts to define distinct disease subtypes, while emphasizing cross-diagnostic and dimensional approaches. In addition, we discuss current challenges in psychoradiology and outline potential future strategies for clinically applicable translation.

Indexed as

BiomarkersBrainHumansMagnetic Resonance ImagingMental DisordersNeuroimagingPsychiatryRadiologySyndromeBiomarkersBiomarkersDisease subtypesMR imagingNeuroimagingPsychiatric disordersPsychoradiology

Identifiers

PMID31759570
PMCPMC6878901

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.