Evidence map›Paper›PMID 31759484›Full record

ArticleKidney international2019

A new mouse model of anti-GBM disease sheds light on maternal transfer of alloantibodies in glomerular disease.

Marina Vivarelli, Francesco Emma

Abstract readComment
PubMed Publisher
In one paragraph

Article in Kidney international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marina VivarelliDivision of Nephrology, Department of Pediatric Subspecialties, Bambino Gesù Children's Hospital - IRCCS, Rome, Italy.
Francesco EmmaDivision of Nephrology, Department of Pediatric Subspecialties, Bambino Gesù Children's Hospital - IRCCS, Rome, Italy. Electronic address: francesco.emma@opbg.net.
Bambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membranous nephropathy and anti-glomerular basement membrane glomerulonephritis are characterized by the deposition of antibodies that recognize specific glomerular epitopes. These antibodies may develop in autoimmune diseases, after exposure to new antigens or after passive maternal transfer, such as in neonatal membranous nephropathy secondary to in utero transfer of anti-neutral endopeptidase protein Igs. In this issue of Kidney International, Abrahamson et al. reported a murine model of passive anti-glomerular basement membrane disease caused by antibody transfer from pregnant mice to their offspring.

Indexed as

Anti-Glomerular Basement Membrane DiseaseGlomerulonephritisAnimalsAutoantibodiesDisease Models, AnimalHumansImmunoglobulin GIsoantibodiesLamininMiceMice, TransgenicAutoantibodiesImmunoglobulin GIsoantibodiesLamininlaminin alpha5

Identifiers

PMID31759484
OpenAlexW2990822046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.