SynthesisAsian Pacific journal of cancer prevention : APJCP2019
Nasopharyngeal Carcinoma (NPC) Risk Factors: A Systematic Review and Meta-Analysis of the Association with Lifestyle, Diets, Socioeconomic and Sociodemographic in Asian Region.
Synthesis in Asian Pacific journal of cancer prevention : APJCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- A Current Perspective of Two of the Most Aggressive Head and Neck Cancers: Pharyngeal and Laryngeal.Current oncology (Toronto, Ont.) · 2025Pooled it
- Risk Factors Associated with Nasopharyngeal Cancer Incidences in Indonesia: A Systematic Review and Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2023Pooled it
- Associations of combined lifestyle and genetic risk with incident head and neck cancer: a prospective study in the UK Biobank.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Article
- Epstein-Barr Virus-Mediated Apoptosis Evasion in Epithelial Malignancies: Molecular Mechanisms and Therapeutic Implications.Biology · 2026Review
- Interaction between human oxoguanine glycosylase 1 gene polymorphisms and smoking status on nasopharyngeal carcinoma risk.Journal of human genetics · 2026Article
- Structural patterns and transcriptional effects of integrated Epstein-Barr Virus revealed by long-read sequencing and RNA-sequencing in nasopharyngeal carcinoma.Virology journal · 2026Article
- Therapeutic Innovations in Nasopharyngeal Carcinoma: Current Strategies and Emerging Perspectives.Life (Basel, Switzerland) · 2026Review
- Review
- Global and regional burden of nasopharyngeal cancer in older adults attributable to smoking and high alcohol use from 1990 to 2021.Frontiers in public health · 2025Article
- Machine learning-based prediction of nasopharyngeal carcinoma risk: a clinical approach.Frontiers in immunology · 2025Article
- Development of a Predictive Model for the Risk of Myelosuppression in Patients With Nasopharyngeal Carcinoma Undergoing Chemoradiotherapy.Clinical Medicine Insights. Oncology · 2025Article
- Gender differences in awareness and practices of cancer prevention recommendations in Korea: a cross-sectional survey.Epidemiology and health · 2025Article
- The protective role of vitamin d in nasopharyngeal carcinoma: insights from Mendelian randomization and meta-analysis.Discover oncology · 2024Article
- Circulating mRNA Expression of VEGF, PTEN, and SOCS1 as Potential Prognostic Predictor for Nasopharyngeal Carcinoma Progression.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Head-to-Head Comparison of [Cancers · 2024Review
- Value of Platelet to Lymphocyte Ratio in Nasopharyngeal Carcinoma Various Stages.Iranian journal of otorhinolaryngology · 2024Article
- Nasopharyngeal carcinoma: current views on the tumor microenvironment's impact on drug resistance and clinical outcomes.Molecular cancer · 2024Review
- A Descriptive, Cross-sectional Study on the Ophthalmic Symptoms and Signs in Patients with Nasopharyngeal Carcinoma.Acta medica Philippina · 2024Article
- A Systematic Review on Clinico-Aetiopathological Trends of Nasopharyngeal Cancer in Asia.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveRisk factors of nasopharyngeal carcinoma (NPC) have been linked with diets, life style and viral<br /> infections. NPC is more rampant in Asian populations than non-Asian countries. Our study aims to assess the validity<br /> of the suggestions provided by multiple case control studies demonstrating that salted fish consumption, smoking and<br /> alcohol consumption are associated with the risk of NPC in Asia.
methodsSearch for related literature on salted fish,<br /> smoking and alcohol consumption were performed via Science Direct, PubMed databases and Google Scholar. Articles<br /> included in this study were from 2009 to 2017, with specific focus on salted fish, smoking and alcohol consumption<br /> as risk factors of NPC. This study excluded all articles published prior to 2009 and articles involving other cancers.<br /> Data were extracted independently by two different researchers and harmonized. Meta-analysis was conducted on the<br /> obtained data, by using R package Meta to create funnel and forest plots.
resultsThe meta-analysis revealed that<br /> salted fish, smoking and alcohol consumption were significantly associated to NPC risk with random effect model score<br /> showing OR of 1.41 at 95% confidence interval (CI) of 1.13-1.75 (P<0.01), OR of 1.89 at 95 % CI of 1.49 - 2.38, and<br /> OR: 1.42 at 95 % CI of 1.23 - 1.65 respectively. Our results also revealed significant association of salted meat, salted<br /> vegetables, house type, wood dust exposure associated with NPC risk with p values less than 0.05.
conclusionThis<br /> study proposes that salted fish intake, smoking and alcohol consumption might be linked to NPC risk in Asians. Further<br /> studies are necessary to ascertain the molecular mechanisms and clarify if the associated path that could function as<br /> therapeutic target.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.