Evidence map›Paper›PMID 31759348›Full record

SynthesisAsian Pacific journal of cancer prevention : APJCP2019

Prevalence of Human Papilloma Virus Sub Genotypes following Head and Neck Squamous Cell Carcinomas in Asian Continent, A Systematic Review Article.

Naeem Bukhari, Joe P Joseph, Sayed Sajid Hussain, Muhammad Adeeb Khan, Marcel Jose Yibirin Wakim, Esam Bashir Yahya, Amina Arif, Afshan Saleem, Nadeem Sharif

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Asian Pacific journal of cancer prevention : APJCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Naeem BukhariCentre for Human Genetics, Hazara University Mansehra, Pakistan.ORCID 0000-0001-5683-8871
Joe P JosephDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, USA.
Sayed Sajid HussainDepartment of Food Science and Engineering, University of Technology PR China.
Muhammad Adeeb KhanDepartment of Zoology, Women University of Azad Jammu and Kashmir, Bagh, Pakistan.
Marcel Jose Yibirin WakimInternal Medicine Department, Central University of Venezuela, Venezuela.
Esam Bashir YahyaDepartment of Microbiology, Faculty of Science, Al Asmarya Islamic University, Zliten, Libya.
Amina ArifFaculty of Life Sciences, University of Central Punjab, Pakistan.
Afshan SaleemDepartment of Microbiology, University of Haripur, Pakistan.
Nadeem SharifDepartment of Medical Laboratory Technology, University of Haripur, Pakistan.
Hazara University · PKUniversity of Azad Jammu and Kashmir · PKUniversity of Central Punjab · PKUniversity of Haripur · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn current era of blue brain intelligence and technology access at ease, standardization of disease etiology demands extensive research to drop-down human papilloma virus associated head and neck squamous cell carcinomas impact at large. Present retrospection aims to estimate comparative association of human papilloma virus sub-genotypes in head and neck squamous cell carcinomas, critical analysis of existing research gap, treatment progress, co-infection, gender association, national status and challenges following Human papilloma virus led head and neck squamous cell carcinomas among world largest continent.

backgroundHead and neck squamous cell carcinomas are not just like malignancies of uterine cervix, lymph nodes and breast cancers. Human papilloma virus led head and neck squamous cell carcinomas treatment directly impact Central nervous system in humans. Intriguingly, human papilloma virus mediated immune response increases patient survival, which indirectly transmit human papilloma virus in future generations and act as a potential threat developing neurogenic disorders.

methodsAn objective based search strategy, following comprehensive and specific search approaches were made to retrieve recent 12 years research data from five different NCBI databases. Out of 300 shortlisted articles, only 24 principal studies met the inclusion criteria.

resultsHighest human papilloma virus prevalence (10.42 %) was found in South Asia, 5.8 % in South East Asia, 5.7 % East Asia, 2.5% in west Asia and no relevant updated data was found from central Asian continent. Highest prevalence (10%) of HPV genotype-16 was recorded in Asia among 3, 710 enrolled cases including 2201 males, 1149 females and 360 cases of unknown gender. While undifferentiated multiple HPV genotype prevalence was 5.5 % (204 cases). Lowest percentage of HPV sub-types 68, 72, 57, 39 were recorded respectively. Pakistan ranked top reporting highest number of HPV-16 cases, Taiwan HPV-18, India HPV-31, Japan HPV-35 and Singapore in HPV-16 and HPV-18 co-infection rates respectively.

conclusionsExact prevalence of HPV associated head and neck squamous cell carcinomas among Asian population is still debatable. Due to higher heterogeneity (P< 0.00001), I2 = 81-88% at 95 % confidence interval), non-availability and limitations of reported studies from Asian sub-continents especially central Asia, western Asia and from south and south east Asia demand large scale collaborative research culture to standardize head and neck squamous cell carcinomas aetiology.<br />.

Indexed as

AsiaAsian PeopleGenotypeHead and Neck NeoplasmsHumansPapillomaviridaePapillomavirus InfectionsPrevalencePrognosisSquamous Cell Carcinoma of Head and NeckCentral AsiaHNSCCsHPVMiddle EastSouth Asia

Identifiers

PMID31759348
PMCPMC7063012
OpenAlexW2990947151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.