Evidence map›Paper›PMID 31759346›Full record

SynthesisAsian Pacific journal of cancer prevention : APJCP2019

Neonatal Weight and Prenatal Exposure to Polychlorinated Biphenyls: A Meta-Analysis.

Hongling Zou, Yinxia Lin, Liu Yang, Chaoyan Ou, Fang Geng, Yao Wang, Wanrong Chen, Yali Niu, Rimei Liang, Qianzi Su and 1 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Asian Pacific journal of cancer prevention : APJCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongling ZouDepartment of Oncology, Second Affiliated Hospital of Guilin Medical College, Guilin, China.
Yinxia LinDepartment of Toxicology, Guilin Medical University School of Public Health, Guilin, China.
Liu YangDepartment of Toxicology, Guilin Medical University School of Public Health, Guilin, China.
Chaoyan OuDepartment of Toxicology, Guilin Medical University School of Public Health, Guilin, China.
Fang GengDepartment of Clinical Laboratory, Tangshan Maternity and Children's Health Care Hospital, Tangshan, Hebei, China.
Yao WangDepartment of Toxicology, Guilin Medical University School of Public Health, Guilin, China.
Wanrong ChenDepartment of Toxicology, Guilin Medical University School of Public Health, Guilin, China.
Yali NiuDepartment of Toxicology, Guilin Medical University School of Public Health, Guilin, China.
Rimei LiangDepartment of Toxicology, Guilin Medical University School of Public Health, Guilin, China.
Qianzi SuDepartment of Toxicology, Guilin Medical University School of Public Health, Guilin, China.
Yi SunDepartment of Toxicology, Guilin Medical University School of Public Health, Guilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis research studied the relationship between maternal exposure to polychlorinated biphenyls and neonatal birth weight through systematic review and meta-analysis of existing literature.

methodsWe searched for all the studies published in MEDLINE / PUBMEDN / EMBASE (Medical Abstract Database) by June 2018, and seven studies had been selected.

resultsThe results showed that there was significant correlation between birth weight reduction and PCBS exposure throughout pregnancy (β=-0.586g, 95%CI:-0.629,-0.543). There was a negative correlation between birth weight and PCBs exposure and umbilical cord serum (β=-0.833g) and maternal serum (β= -0.504g).Subgroup analyses showed significantly different effects of PCBs exposure on birth weight in different regions, stages of pregnancy and study designs. It was thought the heterogeneity was mainly caused by geographical regions, stages of pregnancy, and the assessment methods.

conclusionThe meta analysis revealed a negative correlation between PCBs exposure and birth weight but there was significant difference in the correlation between birth weight loss.

Indexed as

Infant, Low Birth WeightMaternal ExposureEnvironmental PollutantsFemaleHumansInfant, NewbornPolychlorinated BiphenylsPregnancyPrenatal Exposure Delayed EffectsPrognosisEnvironmental PollutantsPolychlorinated BiphenylsBirth weightMeta-analysisPolychlorinated biphenyls

Identifiers

PMID31759346
PMCPMC7063008

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.