Evidence map›Paper›PMID 31759145›Full record

ArticleCellular and molecular gastroenterology and hepatology2020

MYPT1 Down-regulation by Lipopolysaccharide-SIAH1/2 E3 Ligase-Ubiquitin-Proteasomal Degradation Contributes to Colonic Obstruction of Hirschsprung Disease.

W Zhao, P Wang, W He, T Tao, H Li, Y Li, W Jiang, J Sun, X Ge, X Chen and 9 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular gastroenterology and hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

W ZhaoState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China; Reproductive Medical Center, Jinling Hospital Affiliated Medical School of Nanjing University, Nanjing, China.
P WangState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
W HeJiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Soochow University, Suzhou, China.
T TaoState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
H LiDepartment of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Y LiState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
W JiangDepartment of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
J SunState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
X GeDepartment of General Surgery, Sir Run Run Shaw Hospital Affiliated Medical College of Zhejiang University, Hangzhou, China.
X ChenState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
Y ZhengState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
L WeiState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
C ChenState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
Y WangState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
C LiState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.
H ChenCollege of Life Science, Nanjing Normal University, Nanjing, China.
B YaoReproductive Medical Center, Jinling Hospital Affiliated Medical School of Nanjing University, Nanjing, China. Electronic address: yaobing@nju.edu.cn.
W TangDepartment of Pediatric Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China. Electronic address: twbcn@njmu.edu.cn.
M ZhuState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China. Electronic address: zhums@nju.edu.cn.
Nanjing University · CNModel Animal Research Center · CNSecond Affiliated Hospital of Nanjing Medical University · CNNanjing Normal University · CNSoochow University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsColonDisease Models, AnimalDown-RegulationFemaleHirschsprung DiseaseHumansInfantIntestinal ObstructionLaparoscopyLipopolysaccharidesMaleMiceMice, KnockoutMuscle ContractionMuscle, SmoothEDNRB protein, mouseLipopolysaccharidesMyosin-Light-Chain PhosphataseNuclear ProteinsPPP1R12A protein, humanPpp1r12a protein, mouseProteasome Endopeptidase ComplexReceptor, Endothelin BSeven in Absentia ProteinsUbiquitinUbiquitin-Protein Ligases

Identifiers

PMID31759145
PMCPMC6997446
OpenAlexW2991650344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.