ArticleThe Journal of hospital infection2020
Assessment of the potential for pathogen dispersal during high-flow nasal therapy.
Article in The Journal of hospital infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Oxygen Therapy and Risk of Infection for Health Care Workers Caring for Patients With Viral Severe Acute Respiratory Infection: A Systematic Review and Meta-analysis.Annals of emergency medicine · 2021Pooled it
- High-flow nasal cannula for acute hypoxemic respiratory failure in patients with COVID-19: systematic reviews of effectiveness and its risks of aerosolization, dispersion, and infection transmission.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2020Pooled it
- Position Paper for the State-of-the-Art Application of Respiratory Support in Patients with COVID-19.Respiration; international review of thoracic diseases · 2020Guideline
- Assessment of dispersion of airborne particles of oral/nasal fluid by high flow nasal cannula therapy.PloS one · 2021Trial
- Bacterial Community- and Hospital-Acquired Pneumonia in Patients with Critical COVID-19-A Prospective Monocentric Cohort Study.Antibiotics (Basel, Switzerland) · 2024Article
- Current SARS-CoV-2 Protective Strategies for Healthcare Professionals.Biomedicines · 2023Review
- Article
- Characterization of SARS-CoV-2 Aerosols Dispersed During Noninvasive Respiratory Support of Patients With COVID-19.Respiratory care · 2023Article
- Bacterial Resistance to Antibiotics and Clonal Spread in COVID-19-Positive Patients on a Tertiary Hospital Intensive Care Unit, Czech Republic.Antibiotics (Basel, Switzerland) · 2022Article
- High flow nasal cannula for adult acute hypoxemic respiratory failure in the ED setting.The American journal of emergency medicine · 2021Review
- The Role of Noninvasive Respiratory Management in Patients with Severe COVID-19 Pneumonia.Journal of personalized medicine · 2021Review
- Emergency Department Management of Severe Hypoxemic Respiratory Failure in Adults With COVID-19.The Journal of emergency medicine · 2021Review
- Quantitative Assessment of Viral Dispersion Associated with Respiratory Support Devices in a Simulated Critical Care Environment.American journal of respiratory and critical care medicine · 2021Article
- How to deliver aerosolized medications through high flow nasal cannula safely and effectively in the era of COVID-19 and beyond: A narrative review.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2021Review
- COVID-19 Treatment at a Glance.Turkish thoracic journal · 2020Review
- Aerosol Generation from the Respiratory Tract with Various Modes of Oxygen Delivery.American journal of respiratory and critical care medicine · 2020Article
- COVID-19 respiratory support in the emergency department setting.The American journal of emergency medicine · 2020Review
- Surgical mask on top of high-flow nasal cannula improves oxygenation in critically ill COVID-19 patients with hypoxemic respiratory failure.Annals of intensive care · 2020Article
- Aerosol-generating procedures and infective risk to healthcare workers from SARS-CoV-2: the limits of the evidence.The Journal of hospital infection · 2020Review
- Retrospective analysis of high flow nasal therapy in COVID-19-related moderate-to-severe hypoxaemic respiratory failure.BMJ open respiratory research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-flow nasal therapy is increasingly used in hospitals because of its effectiveness and patient comfort. However, pathogens in the patient's nasal and oral cavities may be dispersed by forced air. This study aimed to investigate the risk of pathogen dispersal during high-flow nasal therapy. Liquid and bacterial dispersal were assessed via in-vitro experimental set-ups using a manikin. Thickened water or fresh yeast solution mimicked saliva and nasal mucus secretions. Dispersal was limited to the proximal area of the face and nasal cannula, suggesting that high-flow nasal therapy does not increase the risk of droplet and contact infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.