Evidence map›Paper›PMID 31759092›Full record

Trial reportBrain, behavior, and immunity2020

Feeling needed: Effects of a randomized generativity intervention on well-being and inflammation in older women.

Mona Moieni, Michael R Irwin, Teresa E Seeman, Theodore F Robles, Matthew D Lieberman, Elizabeth C Breen, Stephanie Okimoto, Clara Lengacher, Jesusa M G Arevalo, Richard Olmstead and 2 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Brain, behavior, and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 49 citations in OpenAlex.

  1. Generativity and Social Well-Being in Older Women: Expectations Regarding Aging Matter.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Trial
  2. Article
  3. Article
  4. Article
  5. Associations Between Generativity and Social Asymmetry Among Older Adults in Japan.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Generativity and Gendered Pathways to Health: The Role of Human, Social, and Financial Capital Past Mid-Life.International journal of environmental research and public health · 2022
    Article
  12. A Scoping Review of the Maternal Role at Older Age; Perceptions and Occupations.International journal of environmental research and public health · 2022
    Article
  13. Article
  14. The Type I interferon antiviral gene program is impaired by lockdown and preserved by caregiving.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Mona MoieniDepartment of Psychology, University of California, Los Angeles, CA 90095, USA.
Michael R IrwinDepartment of Psychology, University of California, Los Angeles, CA 90095, USA; Semel Institute for Neuroscience and Human Behavior, Cousins Center for Psychoneuroimmunology, University of California, Los Angeles, CA 90095, USA.
Teresa E SeemanDepartment of Medicine, Division of Geriatrics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Theodore F RoblesDepartment of Psychology, University of California, Los Angeles, CA 90095, USA.
Matthew D LiebermanDepartment of Psychology, University of California, Los Angeles, CA 90095, USA.
Elizabeth C BreenSemel Institute for Neuroscience and Human Behavior, Cousins Center for Psychoneuroimmunology, University of California, Los Angeles, CA 90095, USA.
Stephanie OkimotoUCLA Clinical and Translational Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Clara LengacherDepartment of Psychology, University of California, Los Angeles, CA 90095, USA.
Jesusa M G ArevaloDepartment of Medicine, Division of Hematology-Oncology, and Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA.
Richard OlmsteadSemel Institute for Neuroscience and Human Behavior, Cousins Center for Psychoneuroimmunology, University of California, Los Angeles, CA 90095, USA.
Steven W ColeSemel Institute for Neuroscience and Human Behavior, Cousins Center for Psychoneuroimmunology, University of California, Los Angeles, CA 90095, USA; Department of Medicine, Division of Hematology-Oncology, and Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA.
Naomi I EisenbergerDepartment of Psychology, University of California, Los Angeles, CA 90095, USA. Electronic address: neisenbe@ucla.edu.
University of California, Los Angeles · USSalk Institute for Biological Studies · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
UCLA OLDER AMERICANS INDEPENDENCE CENTERP30AG028748 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MOORE, ALISON AHERN · 2006 to 2017
$9.8M
Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HIRAM BELTRAN-SANCHEZ · 2016 to 2026
$6.9M
Feeling Needed: Effects of Generativity on Health in Lonely Older AdultsR03AG049254 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EISENBERGER, NAOMI ILANA · 2015 to 2016
$154k
Increasing Perceptions of Generativity in Lonely Older AdultsF31AG048668 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MOIENI, MONA · 2014 to 2016
$102k
NCATS NIH HHS UL1 TR000124NIA NIH HHS F31 AG048668NIA NIH HHS P30 AG028748NIA NIH HHS R03 AG049254NICHD NIH HHS P2C HD041022
6 · The paper itself

Abstract

Generativity, or concern for and contribution to the well-being of younger generations, plays an important role in successful aging. The purpose of this study was to develop a novel, writing-based intervention to increase feelings of generativity and test the effect of this intervention on well-being and inflammation in a sample of older women. Participants in this study (n = 73; mean age = 70.9 years, range 60-86 years) were randomly assigned to a 6-week generativity writing condition (writing about life experiences and sharing advice with others) or a control writing condition (neutral, descriptive writing). Self-reported measures of social well-being, mental health, and physical health, as well as objective measures of systemic and cellular levels of inflammation (plasma pro-inflammatory cytokines interleukin-6 and tumor necrosis factor-α; genome-wide RNA transcriptional profiling), were assessed pre- and post-intervention. The generativity intervention led to significant improvements across multiple domains, including increases in participation in social activities, decreases in psychological distress, more positive expectations regarding aging in the physical health domain, and decreases in pro-inflammatory gene expression. Thus, this study provides preliminary evidence for the ability of a novel, low-cost, low-effort intervention to favorably impact inflammation and well-being in older women.

Indexed as

Health StatusIntergenerational RelationsAgedAged, 80 and overAgingFemaleHumansInflammationMiddle AgedPersonal SatisfactionAgingGenerativityInflammationIntervention

Identifiers

PMID31759092
PMCPMC7010547
OpenAlexW2989570384

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.