Evidence map›Paper›PMID 31759034›Full record

ArticleGastrointestinal endoscopy2020

EUS-guided gastroenteric anastomosis as a bridge to definitive treatment in benign gastric outlet obstruction.

Theodore W James, Sydney Greenberg, Ian S Grimm, Todd H Baron

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Gastrointestinal endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05561907 (Enteral Anastomosis for the Treatment of Gastric Outlet Obstruction), which is not on this map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05561907 narecruitingnot on this mapstarted 2022, after this paper: background citation

Enteral Anastomosis for the Treatment of Gastric Outlet Obstruction: A Randomized Controlled Study Comparing Endoscopic Versus Surgical Gastrojejunostomy

TypeinterventionalSponsorNorthwell HealthRan2022 to 2027Enrolled32ConditionsGastric Outlet ObstructionArmsSurgical gastrojejunostomy (SGJ), Endoscopic gastrojejunostomy (EGJ)
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Updated Classification of EUS-Guided Gastroenterostomy Misdeployment.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Endoscopic ultrasound-guided gastroenterostomy: a review.Translational gastroenterology and hepatology · 2025
    Review
  14. Article
  15. [Treatment Strategies for Gastric Cancer Patients with Gastric Outlet Obstruction].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Theodore W JamesDivision of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina, USA.
Sydney GreenbergDepartment of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Ian S GrimmDivision of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina, USA.
Todd H BaronDivision of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina, USA.
University of North Carolina at Chapel Hill · US

Funding

DIGESTIVE DISEASES EPIDEMIOLOGY TRAINING PROGRAMT32DK007634 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1990 to 2026
$7.4M
NIDDK NIH HHS T32 DK007634
6 · The paper itself

Abstract

BACKGROUND AND

aimsBenign gastric outlet obstruction (GOO) has typically been managed surgically. However, many patients are poor operative candidates because of comorbidities. EUS-guided gastroenterostomy (EUS-GE) using lumen-apposing metal stents (LAMSs) has previously demonstrated efficacy as a definitive treatment for benign and malignant GOO; however, limited data exist on use as a bridge to resolution of the obstruction in an attempt to avoid or delay definitive surgery.

methodsA retrospective series of consecutive patients who underwent EUS-GE between January 2013 and July 2019 for benign GOO at a tertiary referral center were included in the study. The primary outcome was the rate of definitive surgery; secondary outcomes included technical success and rate of adverse events.

resultsDuring the study period, 22 patients with benign GOO underwent EUS-GE (40% female; mean age, 54.2 years). The mean procedure time was 66 minutes, and technical success was achieved in 21. Five patients developed recurrent GOO while the LAMS was in place after a mean dwell time of 228 days; 1 patient was converted to surgical GE. LAMSs were removed electively in 18 patients after GOO resolution and a mean dwell time of 270 days; 1 patient developed a recurrent GOO after LAMS removal and was converted to surgical GE. The rate of recurrent GOO after LAMS removal was 5.6%. Three severe adverse events occurred in the cohort.

conclusionsEUS-GE was able to prevent surgery for GOO in 83.3% of cases. LAMSs needed to stay in place for a mean of 8.5 months to allow resolution of GOO, and there was a low rate of recurrent GOO (5.6%) after LAMS removal. Prospective, randomized trials comparing surgical and endoscopic anastomoses are needed in patients with benign causes of GOO.

Indexed as

Gastric Outlet ObstructionAdultAgedAnastomosis, SurgicalEndosonographyFemaleGastroscopyHumansJejunumMaleMiddle AgedProsthesis ImplantationRetrospective StudiesStentsStomachSurgery, Computer-Assisted

Identifiers

PMID31759034
PMCPMC7039740
OpenAlexW2948996526

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.