Evidence map›Paper›PMID 31758773›Full record

ArticleJMIR cardio2018

A Novel Intelligent Two-Way Communication System for Remote Heart Failure Medication Uptitration (the CardioCoach Study): Randomized Controlled Feasibility Trial.

Christophe Jp Smeets, Valerie Storms, Pieter M Vandervoort, Pauline Dreesen, Julie Vranken, Marita Houbrechts, Hanne Goris, Lars Grieten, Paul Dendale

Registry-linked trialAbstract read
In one paragraph

Article in JMIR cardio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03294811 (CARDIOCOACH), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03294811 nacompletednot on this map

CARDIOCOACH: Development of an Intelligent Two-way Communication System to Coach Elderly Patients With Heart Failure in Their Home Situation

TypeinterventionalSponsorHasselt UniversityRan2014 to 2018Enrolled25ConditionsHeart FailureArmsTelemonitoring
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christophe Jp SmeetsDepartment of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium.ORCID http://orcid.org/0000-0002-1746-7585
Valerie StormsMobile Health Unit, Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.ORCID http://orcid.org/0000-0001-9344-0248
Pieter M VandervoortDepartment of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium.ORCID http://orcid.org/0000-0003-3118-7560
Pauline DreesenFuture Health Department, Ziekenhuis Oost-Limburg, Genk, Belgium.ORCID http://orcid.org/0000-0003-4165-6121
Julie VrankenDepartment of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium.ORCID http://orcid.org/0000-0002-2691-0569
Marita HoubrechtsDepartment of Cardiology, Jessa Ziekenhuis, Hasselt, Belgium.ORCID http://orcid.org/0000-0002-0777-1014
Hanne GorisDepartment of Cardiology, Jessa Ziekenhuis, Hasselt, Belgium.ORCID http://orcid.org/0000-0001-5096-9619
Lars GrietenMobile Health Unit, Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.ORCID http://orcid.org/0000-0001-5452-6137
Paul DendaleDepartment of Cardiology, Jessa Ziekenhuis, Hasselt, Belgium.ORCID http://orcid.org/0000-0003-0821-4559

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEuropean Society of Cardiology guidelines for the treatment of heart failure (HF) prescribe uptitration of angiotensin-converting enzyme inhibitors (ACE-I) and β-blockers to the maximum-tolerated, evidence-based dose. Although HF prognosis can drastically improve when correctly implementing these guidelines, studies have shown that they are insufficiently implemented in clinical practice.

objectiveThe aim of this study was to verify whether supplementing the usual care with the CardioCoach follow-up tool is feasible and safe, and whether the tool is more efficient in implementing the guideline recommendations for β-blocker and ACE-I.

methodsA total of 25 HF patients were randomly assigned to either the usual care control group (n=10) or CardioCoach intervention group (n=15), and observed for 6 months. The CardioCoach follow-up tool is a two-way communication platform with decision support algorithms for semiautomatic remote medication uptitration. Remote monitoring sensors automatically transmit patient's blood pressure, heart rate, and weight on a daily basis.

resultsPatients' satisfaction and adherence for medication intake (10,018/10,825, 92.55%) and vital sign measurements (4504/4758, 94.66%) were excellent. However, the number of technical issues that arose was large, with 831 phone contacts (median 41, IQR 32-65) in total. The semiautomatic remote uptitration was safe, as there were no adverse events and no false positive uptitration proposals. Although no significant differences were found between both groups, a higher number of patients were on guideline-recommended medication dose in both groups compared with previous reports.

conclusionsThe CardioCoach follow-up tool for remote uptitration is feasible and safe and was found to be efficient in facilitating information exchange between care providers, with high patient satisfaction and adherence.

trial registrationClinicalTrials.gov NCT03294811; https://clinicaltrials.gov/ct2/show/NCT03294811 (Archived by WebCite at http://www.webcitation.org/6xLiWVsgM).

Indexed as

call centersclinical decision supportdrug monitoringdrug utilizationheart failuretelemedicine

Identifiers

PMID31758773
PMCPMC6834244

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.