Evidence map›Paper›PMID 31758570›Full record

ArticleJournal of surgical oncology2020

Association between patient age and the risk of mortality following local recurrence of a sacral chordoma.

Matthew T Houdek, Mario Hevesi, Joseph H Schwab, Michael J Yaszemski, Anthony M Griffin, John H Healey, Peter C Ferguson, Francis J Hornicek, Patrick J Boland, Franklin H Sim and 2 more

Abstract read
In one paragraph

Article in Journal of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Development and validation of MRI-based radiomics models for predicting recurrence in patients with spine and pelvis chordomas.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Matthew T HoudekDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.ORCID http://orcid.org/0000-0003-0390-1018
Mario HevesiDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Joseph H SchwabDepartment of Orthopaedic Surgery, Orthopaedic Oncology Service, Massachusetts General Hospital, Boston, Massachusetts.
Michael J YaszemskiDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Anthony M GriffinUniversity Musculoskeletal Oncology Unit, Division of Orthopaedic Surgery, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
John H HealeyOrthopaedic Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center and Weill College of Medicine, Cornell University, New York, New York.
Peter C FergusonUniversity Musculoskeletal Oncology Unit, Division of Orthopaedic Surgery, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
Francis J HornicekDepartment of Orthopedic Surgery, University of California Los Angeles, Los Angeles, California.
Patrick J BolandOrthopaedic Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center and Weill College of Medicine, Cornell University, New York, New York.ORCID http://orcid.org/0000-0002-8201-5091
Franklin H SimDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Peter S RoseDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Jay S WunderUniversity Musculoskeletal Oncology Unit, Division of Orthopaedic Surgery, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748NIH Clinical Center #P30 CA008748Wellcome Trust
6 · The paper itself

Abstract

backgroundLocal recurrence (LR) of sacral chordoma is a difficult problem and the mortality risk associated with LR remains poorly described. The purpose of this study was to evaluate the risk of mortality in patients with LR and determine if patient age is associated with mortality.

methodsA total of 218 patients (144 male, 69 female; mean age 59 ± 15 years) with sacrococcygeal chordomas were reviewed. Cumulative incidence functions and competing risks for death due to disease and nondisease mortality were employed to analyze mortality trends following LR.

resultsThe 10-year overall survival (OS) was 55%. Patients with LR had 44% 10-year OS, similar to patients without (59%; P = .38). The 10-year OS between those less than 55 compared with ≥55 years were similar (69% vs 48%; P = .52). The 10-year death due to disease was worse in patients with LR compared with those without (44% vs 84%; P < .001). In patients without LR, patients ≥55 years were 1.6-fold more likely to experience death due to other causes.

conclusionsPatients with an LR are more likely to die due to disease. Advanced patient age was associated with higher all-cause mortality following resection of sacral chordoma. LR of chordoma was associated with increased disease-specific mortality, regardless of age.

Indexed as

local recurrencemortalitypatient agesacral chordoma

Identifiers

PMID31758570
PMCPMC7242148

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.