Evidence map›Paper›PMID 31758418›Full record

ArticleMagma (New York, N.Y.)2020

Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI.

Ilona A Dekkers, Anneloes de Boer, Kaniska Sharma, Eleanor F Cox, Hildo J Lamb, David L Buckley, Octavia Bane, David M Morris, Pottumarthi V Prasad, Scott I K Semple and 11 more

Abstract readConsensus Statement
In one paragraph

Article in Magma (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Navigator-gated free-breathing joint TMagma (New York, N.Y.) · 2026
    Article
  7. Assessing the Impact of Imaging Parameters on MRI Measurement of Kidney TJournal of magnetic resonance imaging : JMRI · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Magnetic resonance imaging of renal oxygenation.Nature reviews. Nephrology · 2025
    Review
  16. Article
  17. Review
  18. T1 Mapping of the Abdomen, From theAJR. American journal of roentgenology · 2025
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Ilona A DekkersDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-3329-0660
Anneloes de BoerDepartment of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Kaniska SharmaDepartment of Biomedical Imaging Sciences, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Eleanor F CoxSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Hildo J LambDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
David L BuckleyDepartment of Biomedical Imaging Sciences, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Octavia BaneDepartment of Radiology, Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
David M MorrisCentre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, Edinburgh, UK.
Pottumarthi V PrasadDepartment of Radiology, Center for Advanced Imaging, NorthShore University Health System, Evanston, IL, USA.
Scott I K SempleCentre for Cardiovascular Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, Edinburgh, UK.
Keith A GillisInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Paul HockingsAntaros Medical, Mölndal, Sweden.
Charlotte BuchananSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Marcos WolfCenter for Medical Physics and Biomedical Engineering, MR-Centre of Excellence, Medical University of Vienna, Vienna, Austria.
Christoffer LaustsenDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Aarhus, Denmark.
Tim LeinerDepartment of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Bryan HaddockDepartment of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet, Copenhagen University Hospital, Glostrup, Denmark.
Johannes M HoogduinDepartment of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Pim PullensDepartment of Radiology, University Hospital Ghent, Ghent, Belgium.
Steven SourbronDepartment of Biomedical Imaging Sciences, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Susan FrancisDepartment of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. susan.francis@nottingham.ac.uk.

Funding

Longitudinal changes in the intra-renal oxygenation by BOLD MRI in patients withR01DK093793 · NIDDK · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI PRASAD, POTTUMARTHI V · 2012 to 2016
$2.3M
Intrarenal Oxygenation: An Early Marker for Risk of Developing AKIR01DK106557 · NIDDK · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI PRASAD, POTTUMARTHI V · 2016 to 2018
$717k
Quantification of Renal Perfusion, Diffusion and Hypoxia Using Advanced MRI Methods for Assessment of Renal Transplant DysfunctionF32DK109591 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BANE, OCTAVIA · 2016 to 2018
$126k
Austrian Science Fund FWF KLI 736Medical Research Council G0701127Medical Research Council MR/R02264X/1NIDDK NIH HHS 1F32DK109591NIDDK NIH HHS F32 DK109591NIDDK NIH HHS R01 DK093793NIDDK NIH HHS R01 DK106557
6 · The paper itself

Abstract

To develop technical recommendations on the acquisition and post-processing of renal longitudinal (T1) and transverse (T2) relaxation time mapping. A multidisciplinary panel consisting of 18 experts in the field of renal T1 and T2 mapping participated in a consensus project, which was initiated by the European Cooperation in Science and Technology Action PARENCHIMA CA16103. Consensus recommendations were formulated using a two-step modified Delphi method. The first survey consisted of 56 items on T1 mapping, of which 4 reached the pre-defined consensus threshold of 75% or higher. The second survey was expanded to include both T1 and T2 mapping, and consisted of 54 items of which 32 reached consensus. Recommendations based were formulated on hardware, patient preparation, acquisition, analysis and reporting. Consensus-based technical recommendations for renal T1 and T2 mapping were formulated. However, there was considerable lack of consensus for renal T1 and particularly renal T2 mapping, to some extent surprising considering the long history of relaxometry in MRI, highlighting key knowledge gaps that require further work. This paper should be regarded as a first step in a long-term evidence-based iterative process towards ever increasing harmonization of scan protocols across sites, to ultimately facilitate clinical implementation.

Indexed as

Delphi TechniqueHumansInterdisciplinary CommunicationKidneyMagnetic Resonance ImagingNephrologySurveys and QuestionnairesTranslational Research, BiomedicalBiomarkersConsensusKidneyMRIStandardizationT1 relaxationT2 relaxation

Identifiers

PMID31758418
PMCPMC7021750

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.