Evidence map›Paper›PMID 31758415›Full record

ArticleProgress in biomaterials2019

Effect of anodized zirconium implants on early osseointegration process in adult rats: a histological and histomorphometric study.

María Florencia Tano de la Hoz, María Rosa Katunar, Ariel González, Andrea Gomez Sanchez, Alcira Ofelia Díaz, Silvia Ceré

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Progress in biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Nanomaterials (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

María Florencia Tano de la HozINTEMA, Applied Electrochemistry Division, National University of Mar del Plata-CONICET, Colón 4302, B7608FDQ, Mar del Plata, Argentine.
María Rosa KatunarINTEMA, Applied Electrochemistry Division, National University of Mar del Plata-CONICET, Colón 4302, B7608FDQ, Mar del Plata, Argentine.
Ariel GonzálezBiology Department, FCEyN, National University of Mar del Plata, Funes 3250, B7602AYJ, Mar del Plata, Argentine.
Andrea Gomez SanchezCIT Villa María-CONICET, Carlos Pellegrini 211, 5900, Villa María, Argentine.
Alcira Ofelia DíazMarine and Coastal Research Institute (IIMyC), Biology Department, FCEyN, National University of Mar del Plata-CONICET, Funes 3250, B7602AYJ, Mar del Plata, Argentine.
Silvia CeréINTEMA, Applied Electrochemistry Division, National University of Mar del Plata-CONICET, Colón 4302, B7608FDQ, Mar del Plata, Argentine. smcere@fi.mdp.edu.ar.ORCID http://orcid.org/0000-0002-4248-5144
Consejo Nacional de Investigaciones Científicas y Técnicas · ARNational University of Mar del Plata · AR

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas PIP 2014-16Universidad Nacional de Mar del Plata Project 15/G331 ING337/12
6 · The paper itself

Abstract

Since surface plays a key role in bioactivity, the response of the host to the biomaterial will determine the success or failure of the prosthesis. The purpose of this study is to make an exhaustive analysis of the histological and histochemical characteristics of new bone tissue around Zr implants anodized at 60 V (Zr60) supported by histomorphometric methods in a rat model. Fibrous tissue was observed around the control implants (Zr0) and osteoblasts were identified on the trabeculae close to the implantation site that showed typical cytological characteristics of active secretory cells, regardless of the surface condition. The histomorphometrical analysis revealed a significant increase in cancellous bone volume, trabecular thickness and in trabecular number together with a decrease in trabecular separation facing Zr60. TRAP staining showed that there was a relative increase in the number of osteoclasts for Zr60. In addition, a larger number of osteoclast with a greater number of nuclei were detected in the tibiae for Zr60. This research demonstrated that the new bone microarchitecture in contact with Zr60 is able to improve the early stages of the osseointegration process and consequently the primary stability of implants which is a crucial factor to reduce recovery time for patients.

Indexed as

AnodizationHistologyHistomorphometryOsseointegrationZirconium implants

Identifiers

PMID31758415
PMCPMC6930317
OpenAlexW2990779309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.