Evidence map›Paper›PMID 31758304›Full record

ArticleArchives of gynecology and obstetrics2020

Long-term evaluation of quality of life and gastrointestinal well-being after segmental colo-rectal resection for deep infiltrating endometriosis (ENDO-RESECT QoL).

Luigi Carlo Turco, Franco Scaldaferri, Vito Chiantera, Stefano Cianci, Alfredo Ercoli, Anna Fagotti, Francesco Fanfani, Gabriella Ferrandina, Nicola Nicolotti, Andrea Tamburrano and 3 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Archives of gynecology and obstetrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03824054 (Evaluation of Quality of Life and Gastrointestinal Well-being in Patients Undergoing Colorectal Resection for Deep Infiltrating Endometriosis. Retrospective Observational Cohort Study), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03824054 completednot on this map

Evaluation of Quality of Life and Gastrointestinal Well-being in Patients Undergoing Colorectal Resection for Deep Infiltrating Endometriosis. Retrospective Observational Cohort Study

TypeobservationalSponsorCatholic University of the Sacred HeartRan2005 to 2018Enrolled50ConditionsEndometriosisArmscolorectal resection
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Luigi Carlo TurcoDivision of Gynecologic Oncology, Fondazione di Ricerca e Cura Giovanni Paolo II, Università Cattolica del Sacro Cuore, Campobasso, Italy. luigicarlo.turco@gmail.com.ORCID http://orcid.org/0000-0002-3000-178X
Franco ScaldaferriMedicina Interna e Gastroenterologia, Area Gastroenterologia ed Oncologia Medica, Dipartimento di Scienze Gastroenterologiche, Endocrino-Metaboliche e Nefro-Urologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Vito ChianteraDivision of Gynecologic Oncology, Università di Palermo, Palermo, Italy.
Stefano CianciDepartment of Women's and Children's Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Alfredo ErcoliDepartment of Human Pathology of the Adult and of the Childhood "Gaetano Barresi", Università di Messina, Messina, Italy.
Anna FagottiDepartment of Women's and Children's Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Francesco FanfaniDepartment of Women's and Children's Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Gabriella FerrandinaDepartment of Women's and Children's Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Nicola NicolottiMedical Management, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Andrea TamburranoMedical Management, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Virginia VargiuDepartment of Women's and Children's Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giovanni ScambiaDepartment of Women's and Children's Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Francesco CosentinoDivision of Gynecologic Oncology, Fondazione di Ricerca e Cura Giovanni Paolo II, Università Cattolica del Sacro Cuore, Campobasso, Italy.
Università Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · ITUniversity of Messina · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesThe primary objective is to assess the long-term quality of life (QoL) and gastrointestinal well-being in patients with endometriosis (DIE) who underwent segmental resection (SR), through specific questionnaires focused on endometriosis and specific gastrointestinal evaluation. The secondary objectives are represented by the evaluation of peri-operative and post-operative outcomes of the procedure.

methodsThis observational cohort study ENDO-RESECT (ClinicalTrials.gov ID: NCT03824054) reports all clinical data about women who underwent SR for DIE between October 2005 and November 2017. In the part of the study dedicated to the QoL assessment, the questionnaires adopted were the Endometriosis Health Profile (EHP30), the Psychological General Well-Being Index and the Hospital Anxiety and Depression Scale, the Gastrointestinal Well-being questionnaire and the Bristol Stool chart. Major post-surgical morbidity and obstetric outcomes were also collected.

results50 women (18% stage III and 82% stage IV rAFS) were considered for enrollment. EHP-30 interpretation demonstrated a significant improvement in all continuous variables, except for fertility concerns. The overall gastrointestinal QoL and most of the specific symptoms improved after surgery. Frequent bowel movements appeared in the 13% of the series not resulting in an impairment of general and gastrointestinal QoL. Constipation remained unchanged. Patients with depressive mood managed with laparoscopy, benefited the most from SR; moreover, patients with multinodular bowel localizations experienced a greater reduction in abdominal pain. Median FU after SR was 42.5 months (range 12-157 months). Only three (6%) cases of late major grade III complications were documented. The pregnancy rate was 50%.

conclusionsImprovement of general QoL and most of gastrointestinal symptoms was documented after SR.

Indexed as

AdolescentAdultCohort StudiesColorectal NeoplasmsEndometriosisFemaleGastrointestinal DiseasesHumansMiddle AgedPostoperative ComplicationsPregnancyQuality of LifeSurveys and QuestionnairesTreatment OutcomeYoung AdultDeep infiltrating endometriosisGastrointestinal symptomsIntestinal endometriosisPersonalized medicineQuality of lifeSegmental colo-rectal resection

Identifiers

PMID31758304
OpenAlexW2990040903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.