ArticleArchives of gynecology and obstetrics2020
Predictive value of serum β-human chorionic gonadotropin for early pregnancy outcomes.
Article in Archives of gynecology and obstetrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05305027 (Single-centre Retrospective Study on the Predictive Value of Sequential Early βHCG Measurements in IVF Pregnancies.), which is not on this map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single-centre Retrospective Study on the Predictive Value of Sequential Early βHCG Measurements in IVF Pregnancies.
Who cites it
16 citing papers in PubMed.
- When to test: defining the earliest reliable time for pregnancy detection and its prognostic value after frozen embryo transfer.AJOG global reports · 2026Article
- Association between urinary hCG trajectories and the risk of miscarriage in women undergoing embryo transfer: a prospective cohort study.Frontiers in endocrinology · 2026Article
- Serum human chorionic gonadotropin can predict live birth 7 days after frozen-thawed blastocyst transfer.F&S reports · 2025Article
- Evaluation of the relationships between beta-human chorionic gonadotropin (β-hCG) blood levels and pregnancy: A retrospective study.Pakistan journal of medical sciences · 2025Article
- Tailoring clinical management after embryo transfer using β-hCG levels in resource-limited settings.Scientific reports · 2025Article
- An individualized risk prediction tool for ectopic pregnancy within the first 10 weeks of gestation based on machine learning algorithms.Frontiers in medicine · 2025Article
- Single day 14 serum hCG values allow prediction of viable pregnancy and are significantly higher in frozen as compared to fresh single blastocyst transfer.Journal of assisted reproduction and genetics · 2024Article
- Combined analysis of estradiol and β-hCG to predict the early pregnancy outcome of FET: a retrospective study.Journal of ovarian research · 2024Article
- Sonographic vascularity indices' study in ectopic pregnancies, after methotrexate treatment.European journal of obstetrics & gynecology and reproductive biology: X · 2024Article
- A novel test device and quantitative colorimetric method for the detection of human chorionic gonadotropin (hCG) based on Au@Zn-salen MOF for POCT applications.RSC advances · 2023Article
- Engineering placenta-like organoids containing endogenous vascular cells from human-induced pluripotent stem cells.Bioengineering & translational medicine · 2023Article
- Construction of machine learning tools to predict threatened miscarriage in the first trimester based on AEA, progesterone and β-hCG in China: a multicentre, observational, case-control study.BMC pregnancy and childbirth · 2022Observational
- Diagnostic value of a single β-hCG test in predicting reproductive outcomes in women undergoing cleavage embryo transfer: a retrospective analysis from a single center.Reproductive health · 2022Article
- The Application of the EP9-A Protocol in the Analysis of the Performance of the Immunofluorescence Assay for HCG Detection.International journal of general medicine · 2021Article
- Clinical Efficacy and Safety Study of Mifepristone with Misoprostol Treatment in Patients with Missed Abortion.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Human Chorionic Gonadotrophin: New Pleiotropic Functions for an "Old" Hormone During Pregnancy.Frontiers in immunology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the relationship between serum β-human chorionic gonadotropin (HCG) levels and early pregnancy outcomes in women who became pregnant using assisted reproductive technologies (ARTs).
methodsIn this study, we retrospectively analyzed 523 pregnancies after ART use, with respect to the early clinical outcomes based on the serum β-HCG levels. The significance of using serum β-HCG levels to predict outcomes in early pregnancy was evaluated by the receiver operating characteristic (ROC) curve and cutoff values of serum β-HCG.
resultsWe found that elevated serum β-HCG levels resulted in decreased biochemical pregnancy rates, increased multiple rates, and decreased ongoing and ectopic pregnancy rates. The cutoff values of serum β-HCG levels for the prediction of biochemical pregnancy were 213.15 IU/L, 986.65 IU/L, and 2206.5 IU/L for singletons, multiples, and twins or triplets, respectively.
conclusionThe serum β-HCG level 14 or 12 days after D3 or D5 embryo transfer (conducted 3 or 5 days after oocyte retrieval), respectively, predicts biochemical/clinical pregnancy and singleton/multiple pregnancy with robust sensitivity and specificity.
Indexed as
Identifiers
31758302What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.