ArticleScientific reports2019
The type-reproduction number of sexually transmitted infections through heterosexual and vertical transmission.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Analysis of human papillomavirus model with vaccination and individual heterogeneity.Infectious Disease Modelling · 2025Article
- Evaluating the global, regional, and national impact of syphilis: results from the global burden of disease study 2019.Scientific reports · 2023Article
- Serious role of non-quarantined COVID-19 patients for random walk simulations.Scientific reports · 2022Article
- Global Emergence and Dissemination of Neisseria gonorrhoeae ST-9363 Isolates with Reduced Susceptibility to Azithromycin.Genome biology and evolution · 2022Article
- The effect of men who have sex with men (MSM) on the spread of sexually transmitted infections.Theoretical biology & medical modelling · 2021Article
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple sexually transmitted infections (STIs) have threatened human health for centuries. Most STIs spread not only through sexual (horizontal) transmission but also through mother-to-child (vertical) transmission. In a previous work (Ito et al. 2019), we studied a simple model including heterosexual and mother-to-child transmission and proposed a formulation of the basic reproduction number over generations. In the present study, we improved the model to take into account some factors neglected in the previous work: adult mortality from infection, infant mortality caused by mother-to-child transmission, infertility or stillbirth caused by infection, and recovery with treatment. We showed that the addition of these factors has no essential effect on the theoretical formulation. To study the characteristics of the epidemic threshold, we derived analytical formulas for three type-reproduction numbers for adult men, adult women and juveniles. Our result indicates that if an efficient vaccine exists for a prevalent STI, vaccination of females is more effective for containment of the STI than vaccination of males, because the type-reproduction number for adult men is larger than that for adult women when they are larger than one.
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