ArticleNature communications2019
SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trapping.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
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Who cites it
63 citing papers in PubMed.
- Modifying Electrochemical Doping in Light-Emitting Electrochemical Cells With Gold Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Reconfigurable Magnetic Nanopore Platform for Selective Trapping.Small science · 2026Article
- Next-Generation SERS Probes: Engineering Hotspots, Intelligent Molecular Targeting, and AI-Driven Spectral Analysis for Emerging Applications.Nanomaterials (Basel, Switzerland) · 2026Review
- Bi-analyte demonstration of non-resonant, single-molecule SERS with isolated lithographic enhancement structures.Scientific reports · 2026Article
- Single-Molecule Peptide Discrimination via Flow-Through SERS and Machine Learning.ACS photonics · 2026Article
- Single-particle surface-enhanced coherent anti-Stokes Raman scattering: Nanoparticle design and mechanism.Science advances · 2026Article
- SERS Cheminformatics: Opportunities for Data-Driven Discovery and Applications.ACS central science · 2025Review
- Single-Molecule Monitoring of Nucleic Acid Dynamics Using Raman Correlation Spectroscopy in Plasmonic Nanowells.ACS nano · 2025Article
- Raman identification of single nucleotides flowing through permeable plasmonic films.Nature communications · 2025Article
- High-Speed Raman Readout of Single Polypeptides via Plasmonic Nanopores.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Single-Molecule SERS Detection of Phosphorylation in Serine and Tyrosine Using Deep Learning-Assisted Plasmonic Nanopore.The journal of physical chemistry letters · 2025Article
- Single-Molecule SERS Discrimination of Proline from Hydroxyproline Assisted by a Deep Learning Model.Nano letters · 2025Article
- Surface-Enhanced Raman Spectroscopy for Biomedical Applications: Recent Advances and Future Challenges.ACS applied materials & interfaces · 2025Review
- In vivo surface-enhanced Raman scattering techniques: nanoprobes, instrumentation, and applications.Light, science & applications · 2025Review
- Angular-Inertia Regulated Stable and Nanoscale Sensing of Single Molecules Using Nanopore-In-A-Tube.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Plasmonic nanoparticle sensors: current progress, challenges, and future prospects.Nanoscale horizons · 2024Review
- Plasmonic Gold Prism Array for Digital Surface-Enhanced Raman Spectroscopy Sensing.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024Article
- Surface-Enhanced Raman Spectroscopy (SERS)-Based Sensors for Deoxyribonucleic Acid (DNA) Detection.Molecules (Basel, Switzerland) · 2024Review
- In-tube micro-pyramidal silicon nanopore for inertial-kinetic sensing of single molecules.Nature communications · 2024Article
- 'When is a hotspot a good nanospot' - review of analytical and hotspot-dominated surface enhanced Raman spectroscopy nanoplatforms.Nanoscale · 2024Review
3 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Surface-enhanced Raman spectroscopy (SERS) sensing of DNA bases by plasmonic nanopores could pave a way to novel methods for DNA analyses and new generation single-molecule sequencing platforms. The SERS discrimination of single DNA bases depends critically on the time that a DNA strand resides within the plasmonic hot spot. In fact, DNA molecules flow through the nanopores so rapidly that the SERS signals collected are not sufficient for single-molecule analysis. Here, we report an approach to control the residence time of molecules in the hot spot by an electro-plasmonic trapping effect. By directly adsorbing molecules onto a gold nanoparticle and then trapping the single nanoparticle in a plasmonic nanohole up to several minutes, we demonstrate single-molecule SERS detection of all four DNA bases as well as discrimination of single nucleobases in a single oligonucleotide. Our method can be extended easily to label-free sensing of single-molecule amino acids and proteins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.