Evidence map›Paper›PMID 31757855›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

The conical shape of DIM lipids promotes

Jacques Augenstreich, Evert Haanappel, Guillaume Ferré, Georges Czaplicki, Franck Jolibois, Nicolas Destainville, Christophe Guilhot, Alain Milon, Catherine Astarie-Dequeker, Matthieu Chavent

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. Article
  3. mSystems · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Protein-Mediated Virulence in Mycobacterium tuberculosis.Advances in experimental medicine and biology · 2026
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Enhancement of mycobacterial pathogenesis by host interferon-γ.Cellular and molecular life sciences : CMLS · 2024
    Article
  20. Host Cell Death and Modulation of Immune Response againstInternational journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

  • Commented on by
    2019
5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jacques AugenstreichInstitut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Université Paul Sabatier, 31400 Toulouse, France.
Evert HaanappelInstitut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Université Paul Sabatier, 31400 Toulouse, France.
Guillaume FerréInstitut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Université Paul Sabatier, 31400 Toulouse, France.
Georges CzaplickiInstitut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Université Paul Sabatier, 31400 Toulouse, France.
Franck JoliboisLaboratoire de Physique et Chimie des Nano-objets, Institut National des Sciences Appliquées, Université de Toulouse, CNRS, Université Paul Sabatier, F-31077 Toulouse, France.
Nicolas DestainvilleLaboratoire de Physique Théorique, Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes, Université de Toulouse, CNRS, Université Paul Sabatier, 31062 Toulouse, France.
Christophe GuilhotInstitut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Université Paul Sabatier, 31400 Toulouse, France.ORCID 0000-0002-8052-4685
Alain MilonInstitut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Université Paul Sabatier, 31400 Toulouse, France; alain.milon@ipbs.fr catherine.astarie-dequeker@ipbs.fr matthieu.chavent@ipbs.fr.ORCID 0000-0001-5692-8201
Catherine Astarie-DequekerInstitut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Université Paul Sabatier, 31400 Toulouse, France; alain.milon@ipbs.fr catherine.astarie-dequeker@ipbs.fr matthieu.chavent@ipbs.fr.
Matthieu ChaventInstitut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Université Paul Sabatier, 31400 Toulouse, France; alain.milon@ipbs.fr catherine.astarie-dequeker@ipbs.fr matthieu.chavent@ipbs.fr.ORCID 0000-0003-4524-4773
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phthiocerol dimycocerosate (DIM) is a major virulence factor of the pathogen

Indexed as

Mycobacterium tuberculosisCell LineCell MembraneHost-Pathogen InteractionsHumansLipidsMacrophagesMolecular Dynamics SimulationNuclear Magnetic Resonance, BiomolecularTuberculosisLipidsphthiocerol dimycocerosatemacrophage infectionmultiscale molecular dynamicsmycobacterial lipids shapenonbilayer membrane structuresolid-state NMR

Identifiers

PMID31757855
PMCPMC6926010
OpenAlexW2990080171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.