Evidence map›Paper›PMID 31757841›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

Preclinical PERCIST and 25% of SUV

Madhusudan A Savaikar, Timothy Whitehead, Sudipta Roy, Lori Strong, Nicole Fettig, Tina Prmeau, Jingqin Luo, Shunqiang Li, Richard L Wahl, Kooresh I Shoghi

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  8. Review
  9. Harnessing preclinical models for the interrogation of ovarian cancer.Journal of experimental & clinical cancer research : CR · 2022
    Review
  10. Deep Learning and Transfer Learning for Malaria Detection.Computational intelligence and neuroscience · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

  • Commented on by
    SUV2020
5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Madhusudan A SavaikarDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Timothy WhiteheadDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Sudipta RoyDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Lori StrongDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Nicole FettigDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Tina PrmeauDivision of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Jingqin LuoDepartment of Surgery, Washington University School of Medicine, St. Louis, Missouri; and.
Shunqiang LiDivision of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Richard L WahlDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Kooresh I ShoghiDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri shoghik@wustl.edu.
Washington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
Washington University PDX Development and Trial Center - Evaluation of Abemaciclib in Combination with Olaparib in Ovarian Cancer and Breast Cancer Patient-derived Xenograft ModelsU54CA224083 · NCI · WASHINGTON UNIVERSITY · PI Brian Andrew Van Tine · 2017 to 2026
$13.0M
Training/DisseminationP41EB025815 · NIBIB · WASHINGTON UNIVERSITY · PI Buck E. Rogers · 2018 to 2026
$12.7M
Project 2 - Radiation-Induced Treatment of Multiple Myeloma using NanoparticlesU54CA199092 · NCI · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2015 to 2019
$11.5M
WASHINGTON UNIVERSITY CO-CLINICAL IMAGING RESEARCH RESOURCEU24CA209837 · NCI · WASHINGTON UNIVERSITY · PI Li Ding, Shunqiang Li · 2017 to 2026
$6.3M
NCI NIH HHS P30 CA091842NCI NIH HHS U24 CA209837NCI NIH HHS U54 CA199092NCI NIH HHS U54 CA224083NIBIB NIH HHS P41 EB025815
6 · The paper itself

Abstract

Numerous recent works highlight the limited utility of established tumor cell lines in recapitulating the heterogeneity of tumors in patients. More realistic preclinical cancer models are thought to be provided by transplantable, patient-derived xenografts (PDXs). The inter- and intratumor heterogeneity of PDXs, however, presents several challenges in developing optimal quantitative pipelines to assess response to therapy. The objective of this work was to develop and optimize image metrics for

Indexed as

Fluorodeoxyglucose F18AnimalsAntineoplastic Combined Chemotherapy ProtocolsHeterograftsHumansMiceNeoplasm TransplantationPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsTriple Negative Breast NeoplasmsFluorodeoxyglucose F18Radiopharmaceuticalsco-clinical trialspatient-derived xenograftsquantitative imagingreproducibilityresponse to therapytriple-negative breast cancer

Identifiers

PMID31757841
PMCPMC7262224
OpenAlexW2990542823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.