Evidence map›Paper›PMID 31757836›Full record

ArticleMolecular cancer research : MCR2020

Bayesian Modeling Identifies PLAG1 as a Key Regulator of Proliferation and Survival in Rhabdomyosarcoma Cells.

Yanbin Zheng, Lin Xu, Mohammed Hassan, Xiaoyun Zhou, Qinbo Zhou, Dinesh Rakheja, Stephen X Skapek

Open access · greenAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Frontiers in cardiovascular medicine · 2026
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  8. GoatAnimals : an open access journal from MDPI · 2023
    Article
  9. Methyltransferase Inhibition Enables TgfMolecular and cellular biology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yanbin ZhengDepartment of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas. Yanbin.Zheng@UTSouthwestern.edu Stephen.Skapek@UTSouthwestern.edu.
Lin XuDepartment of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas.
Mohammed HassanDepartment of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas.
Xiaoyun ZhouDepartment of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas.
Qinbo ZhouDepartment of Population & Data Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Dinesh RakhejaHarold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0001-6888-7902
Stephen X SkapekDepartment of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas. Yanbin.Zheng@UTSouthwestern.edu Stephen.Skapek@UTSouthwestern.edu.
The University of Texas Southwestern Medical Center · USCenter for Cancer and Blood Disorders · US

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MELANIE H. COBB · 2010 to 2026
$53.7M
NCI NIH HHS P30 CA142543
6 · The paper itself

Abstract

We recently developed a novel computational algorithm that incorporates Bayesian methodology to identify rhabdomyosarcoma disease genes whose expression level correlates with copy-number variations, and we identified

Indexed as

AnimalsApoptosisBayes TheoremCell Line, TumorCell ProliferationDNA-Binding ProteinsGene DosageHeterograftsHumansMiceMice, Inbred NODMice, SCIDRhabdomyosarcomaRNA, MessengerSurvival AnalysisDNA-Binding ProteinsPLAG1 protein, humanRNA, Messenger

Identifiers

PMID31757836
PMCPMC7056573
OpenAlexW2991521731

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.