Evidence map›Paper›PMID 31757829›Full record

ArticleApplied and environmental microbiology2020

Short-Chain

Andrea Muras, Celia Mayer, Paz Otero-Casal, Rob A M Exterkate, Bernd W Brandt, Wim Crielaard, Ana Otero, Bastiaan P Krom

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Quorum sensing inFrontiers in oral health · 2025
    Pooled it
  2. [Research Progress on Quorum Sensing-Regulated Oral Microbial Interaction Networks in Periodontitis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Silent signals: howFrontiers in oral health · 2024
    Review
  8. Journal of oral microbiology · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. The quorum quenching enzyme Aii20J modifiesFrontiers in cellular and infection microbiology · 2023
    Article
  14. Review
  15. Article
  16. Biofilm dysbiosis and caries activity: a surface or an individual issue?Journal of applied oral science : revista FOB · 2023
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Andrea MurasDepartamento de Microbioloxía e Parasitoloxía, Facultade de Bioloxía-CIBUS, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Celia MayerDepartamento de Microbioloxía e Parasitoloxía, Facultade de Bioloxía-CIBUS, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Paz Otero-CasalCentro de Salud Santa Comba/Negreira, EOXI Santiago de Compostela, SERGAS, Santiago de Compostela, Spain.
Rob A M ExterkateDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Bernd W BrandtDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Wim CrielaardDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Ana OteroDepartamento de Microbioloxía e Parasitoloxía, Facultade de Bioloxía-CIBUS, Universidade de Santiago de Compostela, Santiago de Compostela, Spain anamaria.otero@usc.es b.krom@acta.nl.
Bastiaan P KromDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands anamaria.otero@usc.es b.krom@acta.nl.
Universidade de Santiago de Compostela · ESVrije Universiteit Amsterdam · NLAcademic Center for Dentistry Amsterdam · NLServicio Gallego de Salud · ESUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acylhomoserine lactones (AHLs), the quorum-sensing (QS) signals produced by a range of Gram-negative bacteria, are involved in biofilm formation in many pathogenic and environmental bacteria. Nevertheless, the current paradigm excludes a role of AHLs in dental plaque formation, while other QS signals, such as AI-2 and autoinducer peptides, have been demonstrated to play an important role in biofilm formation and virulence-related gene expression in oral pathogens. In the present work, we have explored the effect of externally added AHLs on

Indexed as

Bacterial Physiological PhenomenaQuorum SensingAcyl-ButyrolactonesBacteriaBiofilmsCariogenic AgentsDental PlaqueHumansVirulenceAcyl-ButyrolactonesCariogenic Agentsacylhomoserine lactonedental plaqueperiodontitisquorum sensing

Identifiers

PMID31757829
PMCPMC6974637
OpenAlexW2989686922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.