Evidence map›Paper›PMID 31757756›Full record

ArticleMolecular cell2020

Widespread Prion-Based Control of Growth and Differentiation Strategies in Saccharomyces cerevisiae.

Alan K Itakura, Anupam K Chakravarty, Christopher M Jakobson, Daniel F Jarosz

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Yeast Prions: Discovery, Nature, Cellular Manipulation and Implication.Journal of microbiology and biotechnology · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Prions in Microbes: The Least in the Most.Journal of microbiology (Seoul, Korea) · 2023
    Review
  9. Measuring prion propagation in single bacteria elucidates a mechanism of loss.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. How Big Is the Yeast Prion Universe?International journal of molecular sciences · 2023
    Review
  11. Quiescence inAnnual review of genetics · 2022
    Review
  12. Review
  13. Anti-Prion Systems inViruses · 2022
    Review
  14. Article
  15. Article
  16. Protein aggregation and the evolution of stress resistance in clinical yeast.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  17. Review
  18. Article
  19. Review
  20. Protein self-assembly: A new frontier in cell signaling.Current opinion in cell biology · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alan K ItakuraDepartment of Biology, Stanford University, 269 Campus Drive, Stanford, CA 94305, USA; Department of Chemical and Systems Biology, Stanford University, 269 Campus Drive, Stanford, CA 94305, USA.
Anupam K ChakravartyDepartment of Chemical and Systems Biology, Stanford University, 269 Campus Drive, Stanford, CA 94305, USA.
Christopher M JakobsonDepartment of Chemical and Systems Biology, Stanford University, 269 Campus Drive, Stanford, CA 94305, USA.
Daniel F JaroszDepartment of Chemical and Systems Biology, Stanford University, 269 Campus Drive, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, 269 Campus Drive, Stanford, CA 94305, USA. Electronic address: jarosz@stanford.edu.
Stanford University · US

Funding

Supplement to Enhance Wellness and Resiliency in the Graduate EnvironmentT32GM007276 · NIGMS · STANFORD UNIVERSITY · PI MORRISON, ASHBY J. · 1985 to 2023
$32.9M
Brain-wide screen for a neural pacemaker of agingR01AG063418 · NIA · STANFORD UNIVERSITY · PI BRUNET, ANNE, DEISSEROTH, KARL A. · 2018 to 2022
$13.5M
Protein-based Molecular Memories in Gene Regulation, Disease, and DevelopmentDP2GM119140 · NIGMS · STANFORD UNIVERSITY · PI JAROSZ, DANIEL · 2015 to 2015
$2.4M
Epigenetics in the extreme - investigating heritability driven by disordered RNA binding proteins in development and cancerK99GM128180 · NIGMS · STANFORD UNIVERSITY · PI CHAKRAVARTY, ANUPAM KUMAR · 2018 to 2019
$180k
NIA NIH HHS R01 AG063418NIGMS NIH HHS DP2 GM119140NIGMS NIH HHS K99 GM128180NIGMS NIH HHS T32 GM007276
6 · The paper itself

Abstract

Theory and experiments suggest that organisms would benefit from pre-adaptation to future stressors based on reproducible environmental fluctuations experienced by their ancestors, but the mechanisms driving pre-adaptation remain enigmatic. We report that the [SMAUG

Indexed as

Adaptation, PhysiologicalCell DifferentiationCell ProliferationPrionsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsPrionsSaccharomyces cerevisiae ProteinsAdaptive predictionMeiosis/gametogenesisPhenotypic variationTransgenerational inheritance

Identifiers

PMID31757756
PMCPMC6980781
OpenAlexW2989970537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.