ArticleOphthalmology. Retina2020
Longitudinal Detection of Radiation-Induced Peripapillary and Macular Retinal Capillary Ischemia Using OCT Angiography.
Article in Ophthalmology. Retina, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Macular thickness profile in an adult population using Spectralis spectral-domain optical coherence tomography.Scientific reports · 2026Article
- Up to ten years of visual acuity outcomes in fellow eyes post-uveal melanoma treatment with iodine-125 radiotherapy, transpupillary thermotherapy, and proton beam therapy.Journal of contemporary brachytherapy · 2025Article
- Radiation retinopathy following episcleral brachytherapy for intraocular tumors: Current treatment options.Journal of contemporary brachytherapy · 2023Review
- Early anti-VEGF treatment for radiation maculopathy and optic neuropathy: lessons learned.Eye (London, England) · 2023Review
- Efficacy of Prophylactic Anti-VEGF in Preventing Radiation Retinopathy: A Systematic Review and Meta-Analysis.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- Reduced blood flow by laser speckle flowgraphy afterBMC ophthalmology · 2022Article
- Review
- Microvascular and Morphologic Changes of the Macula over Lifetime.Life (Basel, Switzerland) · 2022Article
- Case Report: Optical coherence tomography angiography findings in radiation retinopathy.F1000Research · 2022Article
- Laser speckle flowgraphy findings in a patient with radiation retinopathy.International journal of ophthalmology · 2022Article
- Evaluation of radiation maculopathy after treatment of choroidal melanoma with ruthenium-106 using optical coherence tomography angiography.BMC ophthalmology · 2021Article
- Optical coherence tomography angiography characteristics of choroidal melanoma.Eye (London, England) · 2021Observational
- Temporal Relationship Between Visual Field, Retinal and Microvascular Pathology Following 125I-Plaque Brachytherapy for Uveal Melanoma.Investigative ophthalmology & visual science · 2021Article
- OCT Angiography Analysis of Retinal and Choroidal Flow after Proton Beam Therapy for Choroidal Melanoma.Ophthalmology scienceArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo study longitudinal changes in retinal capillary circulation in eyes treated with iodine 125 (I
designLongitudinal prospective study of 21 patients undergoing treatment for uveal melanoma with I
participantsAfter institutional review board approval, participants were enrolled prospectively from an academic ocular oncology clinic.
methodsPeripapillary (4.5 × 4.5-mm) and macular (3 × 3-mm) OCTA scans were acquired with AngioVue (Optovue, Inc, Fremont, CA).
main outcome measuresThe peripapillary nerve fiber layer plexus capillary density (NFLP_CD), macular superficial vascular complex vessel density (mSVC_VD), and foveal avascular zone (FAZ) area were calculated.
resultsBefore treatment, no significant difference was found in the NFLP_CD, mSVC_VD, or FAZ area between eyes with melanoma and normal fellow eyes. By 24 months, 11 eyes had developed clinical signs of radiation retinopathy, radiation optic neuropathy, or both. In treated eyes, the NFLP_CD (48.4±4.1%) was reduced at 12 months (46.7±5.0%; P = 0.04, Wilcoxon signed-rank test) and 24 months (44.5±6.1%; P < 0.001). Similarly, the mSVC_VD (48.4 2±3.6%) was reduced in treated eyes at 12 months (43.5±5.9%; P = 0.01) and 24 months (37.4±9.1%; P < 0.001). The FAZ area (0.26±0.11 mm
conclusionsOCT angiography demonstrated early emergence of peripapillary and macular capillary vasculature changes after I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.