Evidence map›Paper›PMID 31757604›Full record

ArticleNeuron2020

Natural Variation in a Dendritic Scaffold Protein Remodels Experience-Dependent Plasticity by Altering Neuropeptide Expression.

Isabel Beets, Gaotian Zhang, Lorenz A Fenk, Changchun Chen, Geoffrey M Nelson, Marie-Anne Félix, Mario de Bono

Abstract read
In one paragraph

Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  5. Review
  6. Review
  7. Article
  8. Differential processing of a chemosensory cue across life stages sharing the same valence state inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Article
  11. Article
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  13. Review
  14. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Isabel BeetsCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Gaotian ZhangInstitut de Biologie de l'École Normale Supérieure, CNRS, Inserm, PSL Research University, Paris 75005, France.
Lorenz A FenkCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Changchun ChenCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Geoffrey M NelsonCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
Marie-Anne FélixInstitut de Biologie de l'École Normale Supérieure, CNRS, Inserm, PSL Research University, Paris 75005, France. Electronic address: felix@biologie.ens.fr.
Mario de BonoCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK. Electronic address: mdebono@ist.ac.at.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Medical Research Council MC_U105178786NIH HHS P40 OD010440
6 · The paper itself

Abstract

The extent to which behavior is shaped by experience varies between individuals. Genetic differences contribute to this variation, but the neural mechanisms are not understood. Here, we dissect natural variation in the behavioral flexibility of two Caenorhabditis elegans wild strains. In one strain, a memory of exposure to 21% O

Indexed as

AnimalsAnimals, Genetically ModifiedArousalBehavior, AnimalCaenorhabditis elegansCaenorhabditis elegans ProteinsCarbon DioxideDendritesFemaleIndividualityNeuronal PlasticityNeuropeptidesPhosphoric Diester HydrolasesPolymorphism, GeneticSensory Receptor CellsSignal TransductionCaenorhabditis elegans ProteinsCarbon DioxideNeuropeptidesPhosphoric Diester HydrolasesCaenorhabditis elegans, carbon dioxide sensingexperience-dependent plasticitygenetic accommodationnatural variationneuropeptideoxygen sensing

Identifiers

PMID31757604
PMCPMC6953435

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.