Evidence map›Paper›PMID 31757261›Full record

ArticleJournal of substance abuse treatment2019

Differential adoption of opioid agonist treatments in detoxification and outpatient settings.

Kelly E Dunn, Andrew S Huhn, Eric C Strain

Open access · greenAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kelly E DunnJohns Hopkins University School of Medicine, United States of America. Electronic address: kdunn9@jhmi.edu.
Andrew S HuhnJohns Hopkins University School of Medicine, United States of America.
Eric C StrainJohns Hopkins University School of Medicine, United States of America.
Johns Hopkins Medicine · US

Funding

Using Cannabinoids to Enhance Opioid Analgesic Effects in HumansR01DA040644 · NIDA · JOHNS HOPKINS UNIVERSITY · PI CAMPBELL, CLAUDIA MICHELLE, DUNN, KELLY E · 2016 to 2021
$3.4M
A118G SNP and OPRM1 Gene Opioid-Mediated Effects in HumansR01DA035246 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DUNN, KELLY E · 2014 to 2018
$3.2M
Opioid and cannabinoid combinations in laboratory and clinical painR01DA042751 · NIDA · JOHNS HOPKINS UNIVERSITY · PI CAMPBELL, CLAUDIA MICHELLE, DUNN, KELLY E · 2017 to 2020
$2.2M
Evaluating Suvorexant for Sleep Disturbance in Opioid Use DisorderUG3DA048734 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DUNN, KELLY E, HUHN, ANDREW S · 2019 to 2020
$2.2M
Developing a Method to Empirically-evaluate Treatment for Pain within Opioid Maintenance PatientsR34DA042926 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DUNN, KELLY E · 2017 to 2019
$694k
NIDA NIH HHS R01 DA035246NIDA NIH HHS R01 DA040644NIDA NIH HHS R01 DA042751NIDA NIH HHS R34 DA042926NIDA NIH HHS UG3 DA048734
6 · The paper itself

Abstract

backgroundOpioid use disorder (OUD) is a significant public health problem for which a substantial amount of treatment exists. The degree to which methadone and buprenorphine are administered in different treatment modalities is not clear but critical to understanding treatment success rates and service development strategies.

methodsData from the national Treatment Episode Dataset for Admissions and Discharges (TEDS-A [N = 4,070,264] and TEDS-D [832,731], respectively) were used to determine the likelihood patients initiating detoxification and outpatient OUD treatment between 2006 and 2015 were expected to receive opioid agonist treatment. Joinpoint regression evaluated significant trends and a generalized linear model with logit link function identified characteristics associated with receiving an agonist during detoxification. TEDS-D informed the percent of patients leaving detoxification against medical advice who did/did not receive an opioid agonist.

resultsThough agonist use in outpatient settings increased by 60% during 2012-2015, agonist use in detoxification was lower than outpatient treatment, decreased significantly by 26% from 2009 to 2015, and never exceeded 16% of detoxification admissions during 2006-2015. In 2015, persons who were under 25, homeless, had co-occurring psychiatric problems, utilized Medicare, Medicaid, or had no insurance, and had no prior OUD treatment or were high treatment utilizers were the least likely to receive an agonist during detoxification.

conclusionsEfforts to expand opioid agonist access has been successful for outpatient but not detoxification settings. Improving detoxification outcomes is a potentially high impact way for the US to expand efficacious OUD treatment access in the US.

Indexed as

AdultAge FactorsAmbulatory CareAnalgesics, OpioidComorbidityDatasets as TopicFemaleHumansIll-Housed PersonsMaleMedicaidMedicareOpiate Substitution TreatmentOpioid-Related DisordersOutcome and Process Assessment, Health CarePatient Acceptance of Health CareAnalgesics, OpioidBuprenorphineMethadoneOpioidTEDSWithdrawal

Identifiers

PMID31757261
PMCPMC6948179
OpenAlexW2981676636

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.