Evidence map›Paper›PMID 31757097›Full record

ArticleMolecules (Basel, Switzerland)2019

Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles.

Zeshu Dai, Qingqiang Tian, Yanwu Li, Suqin Shang, Wen Luo, Xuetong Wang, Dan Li, Ying Zhang, Zhiyao Li, Jianyong Yuan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zeshu DaiDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Qingqiang TianDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Yanwu LiDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Suqin ShangDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Wen LuoDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Xuetong WangDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Dan LiDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Ying ZhangDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Zhiyao LiDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Jianyong YuanDepartment of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.

Funding

Chongqing Science and Technology Commission Project of china cstc2018jscx-msybx0294
6 · The paper itself

Abstract

An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures.

Indexed as

Heterocyclic CompoundsImidazolesHeterocyclic CompoundsimidazoleImidazolesamino deprotectionamino protectionimidazolium chlorideMichael addition reactionseven-membered ringsolvent-free

Identifiers

PMID31757097
PMCPMC6930643

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.