Evidence map›Paper›PMID 31757015›Full record

ArticleInternational journal of molecular sciences2019

Altered Genome-Wide DNA Methylation in Peripheral Blood of South African Women with Gestational Diabetes Mellitus.

Stephanie Dias, Sumaiya Adam, Paul Rheeder, Johan Louw, Carmen Pheiffer

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Observational
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  20. Epigenetic Alterations Related to Gestational Diabetes Mellitus.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie DiasBiomedical Research and Innovation Platform (BRIP), South African Medical Research Council, P.O. Box 19070, Tygerberg, Cape Town 7505, South Africa.ORCID 0000-0003-3008-4279
Sumaiya AdamDepartment of Obstetrics and Gynecology, University of Pretoria, Private Bag X169, Pretoria 0001, South Africa.ORCID 0000-0001-8769-3273
Paul RheederDepartment of Internal Medicine, Faculty of Health Sciences, University of Pretoria, Private Bag X169, Pretoria 0001, South Africa.
Johan LouwBiomedical Research and Innovation Platform (BRIP), South African Medical Research Council, P.O. Box 19070, Tygerberg, Cape Town 7505, South Africa.
Carmen PheifferBiomedical Research and Innovation Platform (BRIP), South African Medical Research Council, P.O. Box 19070, Tygerberg, Cape Town 7505, South Africa.ORCID 0000-0002-0707-1552

Funding

National Research Foundation 99391South African Medical Research Council baseline funding
6 · The paper itself

Abstract

Increasing evidence implicate altered DNA methylation in the pathophysiology of gestational diabetes mellitus (GDM). This exploratory study probed the association between GDM and peripheral blood DNA methylation patterns in South African women. Genome-wide DNA methylation profiling was conducted in women with (

Indexed as

DNA MethylationAdultBiomarkersCalcium-Binding ProteinsCpG IslandsDiabetes, GestationalFemaleGenome, HumanHumansPregnancySouth AfricaTrans-ActivatorsBiomarkersCalcium-Binding ProteinsCAMTA1 protein, humanTrans-ActivatorsDNA methylationgestational diabetes mellitusMethylationEPIC Bead Chip Arraymolecular biomarkersSouth Africa

Identifiers

PMID31757015
PMCPMC6928622

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.