Evidence map›Paper›PMID 31757005›Full record

ArticleInternational journal of molecular sciences2019

Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.

Olof Eriksson, Ram Kumar Selvaraju, Marie Berglund, Daniel Espes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olof ErikssonScience for Life Laboratory, Department of Medicinal Chemistry, Division of Molecular Imaging, Uppsala University, 75123 Uppsala, Sweden.
Ram Kumar SelvarajuScience for Life Laboratory, Department of Medicinal Chemistry, Division of Molecular Imaging, Uppsala University, 75123 Uppsala, Sweden.
Marie BerglundDepartment of Public Health and Caring Sciences, Uppsala University, 75237 Uppsala, Sweden.
Daniel EspesDepartment of Medical Sciences, Uppsala University, 75185 Uppsala, Sweden.

Funding

ExoDiab N/AFredrik och Ingrid Thurings Stiftelse N/AMagnus Bergvalls Stiftelse N/AScience for Life Laboratory N/ASEB Diabetesfonden N/ATurku Center of Excellence in Metabolic Imaging N/A
6 · The paper itself

Abstract

Type 1 diabetes (T1D) is characterized by the loss of insulin-producing cells and hence insulin secretion and metabolic control. In addition to insulin, there are a number of hormones and cytokines that influence metabolism, and many of these can be secreted from brown adipose tissue (BAT). However, the presence and activity of BAT in T1D have not been studied, despite the fact that preclinical studies have shown that transplantation of BAT in mouse models of T1D can restore metabolic control. The metabolic activity of BAT, white adipose tissue (WAT), and skeletal muscle was investigated in patients with T1D (

Indexed as

Adipose Tissue, BrownAdultDiabetes Mellitus, Type 1FemaleFluorodeoxyglucose F18GlucoseHumansMaleMuscle, SkeletalPositron Emission Tomography Computed TomographyRadiopharmaceuticalsFluorodeoxyglucose F18GlucoseRadiopharmaceuticalsbrown adipose tissuemetabolic controlpositron emission tomographytype 1 diabetes

Identifiers

PMID31757005
PMCPMC6928828

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.