Evidence map›Paper›PMID 31756937›Full record

ReviewAntioxidants (Basel, Switzerland)2019

Bee Collected Pollen and Bee Bread: Bioactive Constituents and Health Benefits.

Rodica Mărgăoan, Mirela Stranț, Alina Varadi, Erkan Topal, Banu Yücel, Mihaiela Cornea-Cipcigan, Maria G Campos, Dan C Vodnar

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Compositional and Biofunctional Properties ofFoods (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
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  11. Review
  12. Article
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  14. Article
  15. Article
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  18. Article
  19. Article
  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rodica MărgăoanAdvanced Horticultural Research Institute of Transylvania, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania.
Mirela StranțAssociation Health with CasaBIO, 400015 Cluj-Napoca, Romania.
Alina VaradiAssociation Health with CasaBIO, 400015 Cluj-Napoca, Romania.
Erkan TopalApiculture Section, Aegean Agricultural Research Institute, İzmir 35661, Turkey.
Banu YücelDepartment of Animal Science, Faculty of Agriculture, Ege University, İzmir 35100, Turkey.
Mihaiela Cornea-CipciganFaculty of Horticulture, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania.
Maria G CamposObservatory of Drug-Herb Interactions, Faculty of Pharmacy, University of Coimbra, Heath Sciences Campus, Azinhaga de Santa Comba, 3000-370 Coimbra, Portugal.
Dan C VodnarDepartment of Food Science, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania.

Funding

National Research Development Projects to finance excellence (PFE)-37/2018-2020
6 · The paper itself

Abstract

Bee products were historically used as a therapheutic approach and in food consumption, while more recent data include important details that could validate them as food supplements due to their bioproperties, which support their future use as medicines. In this review data, data collected from bee pollen (BP) and bee bread (BB) essays will be discussed and detailed for their nutritional and health protective properties as functional foods. Dietary antioxidants intake derived from BP and BB have been associated with the prevention and clinical treatment of multiple diseases. The beneficial effects of BP and BB on health result from the presence of multiple polyphenols which possess anti-inflammatory properties, phytosterols and fatty acids, which play anticancerogenic roles, as well as polysaccharides, which stimulate immunological activity. From the main bioactivity studies with BP and BB, in vitro studies and animal experiments, the stimulation of apoptosis and the inhibition of cell proliferation in multiple cell lines could be one of the major therapeutic adjuvant effects to be explored in reducing tumor growth. Tables summarizing the main data available in this field and information about other bio-effects of BP and BB, which support the conclusions, are provided. Additionally, a discussion about the research gaps will be presented to help further experiments that complete the tree main World Health Organization (WHO) Directives of Efficiency, Safety and Quality Control for these products.

Indexed as

antioxidant activitybee breadbee pollencancerdiseaseshealthnatural product

Identifiers

PMID31756937
PMCPMC6943659

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.