Evidence map›Paper›PMID 31756754›Full record

ArticleAmerican journal of perinatology2021

Antenatal Fetal Adrenal Measurements at 22 to 30 Weeks' Gestation, Fetal Growth Restriction, and Perinatal Morbidity.

Nathan R Blue, Matthew Hoffman, Amanda A Allshouse, William A Grobman, Hyagriv N Simhan, Ozhan M Turan, Samuel Parry, Judith H Chung, Uma Reddy, David M Haas and 4 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in American journal of perinatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 1 country.

Nathan R BlueDepartment of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah.ORCID 0000-0003-2187-3428
Matthew HoffmanDepartment of Obstetrics and Gynecology, Christiana Care Health System, Wilmington, Delaware.ORCID 0000-0002-2927-8693
Amanda A AllshouseDepartment of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah.
William A GrobmanDepartment of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois.
Hyagriv N SimhanDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania.
Ozhan M TuranDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland.
Samuel ParryDepartment of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania.
Judith H ChungDepartment of Obstetrics and Gynecology, University of California, Irvine, Orange, California.
Uma ReddyDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, Yale University, New Haven, Connecticut.
David M HaasDepartment of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana.
Stephen MyersDepartment of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, Kansas.
Brian MercerDepartment of Obstetrics and Gynecology, MetroHealth Medical Center, Cleveland, Ohio.
George R SaadeDepartment of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas.
Robert M SilverDepartment of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah.
University of Utah · USChristiana Care Health System · USIndiana University School of MedicineMagee-Womens Hospital · USMetroHealth · USNorthwestern University · USThe University of Texas Medical Branch at Galveston · USUniversity of California, Irvine · USUniversity of Kansas Medical Center · USUniversity of Maryland, Baltimore · USUniversity of Pennsylvania · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD087230 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HYAGRIV N SIMHAN · 2016 to 2026
$3.2M
Utah Women's Reproductive Health Research Career Development ProgramK12HD085816 · NICHD · UNIVERSITY OF UTAH · PI SILVER, ROBERT M. · 2015 to 2024
$3.2M
Prevention of Preterm Birth in high Risk Nulliparous PatientsU10HD063047 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WAPNER, RONALD · 2010 to 2014
$1.9M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063053 · NICHD · UNIVERSITY OF UTAH · PI SILVER, ROBERT M. · 2010 to 2014
$1.7M
Preterm Birth in Nulliparous Women: An Understudied Population at Great Risk U10HD063020 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GROBMAN, WILLIAM ADAM · 2010 to 2014
$1.6M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063046 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI WING, DEBORAH A · 2010 to 2014
$1.6M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063041 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SIMHAN, HYAGRIV N · 2010 to 2014
$1.5M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063048 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI PARRY, SAMUEL I. · 2010 to 2014
$1.5M
Dissecting the Genetic Etiology of Preterm Birth in Nulliparous WomenU10HD063037 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI HAAS, DAVID M. · 2010 to 2014
$1.2M
Adverse Outcomes in Nulliparous Pregnancies: The Ohio CollaborativeU10HD063072 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI MERCER, BRIAN M. · 2010 to 2014
$1.2M
The Fetal Adrenal Gland as a Predictor of Spontaneous Preterm BirthR21HD068809 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HOFFMAN, MATTHEW KENDALL, WAPNER, RONALD · 2011 to 2012
$557k
NCATS NIH HHS UL1 TR001863NICHD NIH HHS K12 HD085816NICHD NIH HHS R21 HD068809NICHD NIH HHS U10 HD063020NICHD NIH HHS U10 HD063037NICHD NIH HHS U10 HD063041NICHD NIH HHS U10 HD063046NICHD NIH HHS U10 HD063047NICHD NIH HHS U10 HD063048NICHD NIH HHS U10 HD063053NICHD NIH HHS U10 HD063072NICHD NIH HHS UG1 HD087230
6 · The paper itself

Abstract

objectiveOur objective was to test the association of fetal adrenal size with perinatal morbidity among fetuses with fetal growth restriction (FGR; estimated fetal weight [EFW] < 10th percentile). STUDY

designThis was a secondary analysis of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b) adrenal study, which measured fetal adrenal gland size at 22 to 30 weeks' gestation. We analyzed the transverse adrenal area (TAA) and fetal zone area (absolute measurements and corrected for fetal size) and the ratio of the fetal zone area to the total transverse area using a composite perinatal outcome of stillbirth, neonatal intensive care unit admission, respiratory distress syndrome, necrotizing enterocolitis, retinopathy of prematurity, sepsis, mechanical ventilation, seizure, or death. Among fetuses with FGR, adrenal measurements were compared between those that did and did not experience the composite perinatal outcome.

resultsThere were 1,709 eligible neonates. Seven percent (

conclusionIn our cohort, adrenal size was not associated with risk of morbidity among fetuses with FGR.

Indexed as

Fetal WeightAdolescentAdrenal GlandsAdultCohort StudiesFemaleFetal Growth RetardationGestational AgeHumansInfant, NewbornLogistic ModelsMalePlacental InsufficiencyPregnancyPregnancy OutcomeUltrasonography, Prenatal

Identifiers

PMID31756754
PMCPMC7708295
OpenAlexW2990344569

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.