Evidence map›Paper›PMID 31756539›Full record

ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2020

Unlicensed Umbilical Cord Blood Units Provide a Safe and Effective Graft Source for a Diverse Population: A Study of 2456 Umbilical Cord Blood Recipients.

Karen Ballen, Brent R Logan, Pintip Chitphakdithai, Michelle Kuxhausen, Stephen R Spellman, Alexia Adams, Rebecca J Drexler, Merry Duffy, Ann Kemp, Roberta King and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  7. Infusion of Non-HLA-Matched Off-the-ShelfFrontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 1 country.

Karen BallenUniversity of Virginia Health Center, Charlottesville, Virginia.
Brent R LoganCenter for International Blood and Marrow Transplant Research, Division of Biostatistics, Medical College of Wisconsin, Milwaukee, Wisconsin.
Pintip ChitphakdithaiCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
Michelle KuxhausenCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
Stephen R SpellmanCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, Minnesota. Electronic address: sspellma@nmdp.org.
Alexia AdamsCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
Rebecca J DrexlerCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
Merry DuffyNational Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
Ann KempNational Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
Roberta KingCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
Aleksandar BabicSt. Louis Cord Blood Bank, St. Louis, Missouri.
Colleen DelaneyFred Hutchinson Cancer Research Center, Seattle, Washington.
Chatchada KaranesCity of Hope, Duarte, California.
Joanne KurtzbergCarolinas Cord Blood Bank, Durham, North Carolina; Duke University Medical Center, Durham, North Carolina.
Lawrence PetzStemCyte International Cord Blood Center, Los Angeles, California.
Andromachi ScaradavouNew York Blood Center National Cord Blood Program, New York, New York; Memorial Sloan Kettering Cancer Center, New York, New York.
Elizabeth J ShpallMD Anderson Cancer Center, Houston, Texas.
Clayton SmithUniversity of Colorado Hospital, Aurora, Colorado.
Dennis L ConferCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
John P MillerNational Marrow Donor Program/Be The Match, Minneapolis, Minnesota.
National Marrow Donor Program · USCity of Hope · USDuke Medical Center · USFred Hutch Cancer Center · USHealth Center · USMedical College of Wisconsin · USNew York Blood Center · USThe University of Texas MD Anderson Cancer Center · USUniversity of Colorado Hospital · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
Easy-to-read Informed Consent for HCT Clinical TrialsU10HL069294 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HOROWITZ, MARY MARESCA · 2011 to 2016
$43.8M
NCI NIH HHS P30 CA008748NCI NIH HHS U24 CA076518NHLBI NIH HHS U10 HL069294
6 · The paper itself

Abstract

Umbilical cord blood (UCB) transplantation (UCBT) is a curative procedure for patients with hematologic malignancies and genetic disorders and expands access to transplantation for non-Caucasian patients unable to find a fully matched unrelated donor. In 2011, the US Food and Drug Administration required that unrelated UCBT be performed using either licensed UCB or unlicensed UCB under the Investigational New Drug (IND) program. The National Marrow Donor Program manages an IND under which 2456 patients (1499 adults and 957 children, 564 with malignant diseases and 393 with nonmalignant diseases) underwent single or double UCBT between October 2011 and December 2016. The median patient age was 31 years (range, <1 to 81 years), and 50% of children and 36% of adults were non-Caucasian. The median time to neutrophil engraftment (ie, absolute neutrophil count ≥500/mm

Indexed as

Cord Blood Stem Cell TransplantationGraft vs Host DiseaseHematologic NeoplasmsHematopoietic Stem Cell TransplantationAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFetal BloodHumansInfantMiddle AgedYoung AdultCord blood transplantationLeukemiaLicensureNonmalignant disease

Identifiers

PMID31756539
PMCPMC7198366
OpenAlexW2990203465

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.