Evidence map›Paper›PMID 31756340›Full record

ArticleJournal of theoretical biology2020

On Markov blankets and hierarchical self-organisation.

Ensor Rafael Palacios, Adeel Razi, Thomas Parr, Michael Kirchhoff, Karl Friston

Abstract read
In one paragraph

Article in Journal of theoretical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

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  10. The QBIT Theory of Consciousness: Information, Correlation, and Coherence.Integrative psychological & behavioral science · 2024
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  12. Review
  13. The Universal Optimism of the Self-Evidencing Mind.Entropy (Basel, Switzerland) · 2024
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  14. The Human Affectome.Neuroscience and biobehavioral reviews · 2024
    Review
  15. Article
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  17. Federated inference and belief sharing.Neuroscience and biobehavioral reviews · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ensor Rafael PalaciosThe Wellcome Centre for Human Neuroimaging, University College London, Queen Square, London WC1N 3BG, UK. Electronic address: ensorrafael.palacios@bristol.ac.uk.
Adeel RaziThe Wellcome Centre for Human Neuroimaging, University College London, Queen Square, London WC1N 3BG, UK; Monash Institute of Cognitive and Clinical Neurosciences and Monash Biomedical Imaging, Monash University, Clayton, Australia; Department of Electronic Engineering, NED University of Engineering and Technology, Karachi, Pakistan.
Thomas ParrThe Wellcome Centre for Human Neuroimaging, University College London, Queen Square, London WC1N 3BG, UK.
Michael KirchhoffDepartment of Philosophy, Faculty of Law, Humanities and the Arts, University of Wollongong, Wollongong 2500, Australia.
Karl FristonThe Wellcome Centre for Human Neuroimaging, University College London, Queen Square, London WC1N 3BG, UK.

Funding

Wellcome Trust 088130/Z/09/Z
6 · The paper itself

Abstract

Biological self-organisation can be regarded as a process of spontaneous pattern formation; namely, the emergence of structures that distinguish themselves from their environment. This process can occur at nested spatial scales: from the microscopic (e.g., the emergence of cells) to the macroscopic (e.g. the emergence of organisms). In this paper, we pursue the idea that Markov blankets - that separate the internal states of a structure from external states - can self-assemble at successively higher levels of organisation. Using simulations, based on the principle of variational free energy minimisation, we show that hierarchical self-organisation emerges when the microscopic elements of an ensemble have prior (e.g., genetic) beliefs that they participate in a macroscopic Markov blanket: i.e., they can only influence - or be influenced by - a subset of other elements. Furthermore, the emergent structures look very much like those found in nature (e.g., cells or organelles), when influences are mediated by short range signalling. These simulations are offered as a proof of concept that hierarchical self-organisation of Markov blankets (into Markov blankets) can explain the self-evidencing, autopoietic behaviour of biological systems.

Indexed as

EntropyActive inferenceDynamical systemsFree energyMarkov blanketSelf-organisation

Identifiers

PMID31756340
PMCPMC7284313

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.