Evidence map›Paper›PMID 31756242›Full record

ArticlePloS one2019

Factors affecting acceptance of at-birth point of care HIV testing among providers and parents in Kenya: A qualitative study.

Catherine Wexler, May Maloba, Melinda Brown, Natabhona Mabachi, Kathy Goggin, Brad Gautney, Beryne Odeny, Sarah Finocchario-Kessler

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03435887 (Piloting At-birth Point of Care HIV Testing Strategies in Kenya), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03435887 nacompletednot on this map

Piloting At-birth Point of Care HIV Testing Strategies in Kenya

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2016 to 2020Enrolled1,999ConditionsHIV InfectionsArmsAlere q HIV-1/2 Detect for point of care infant testing, GeneXpert HIV-1 Qual for point of care infant testing, HIV DNA PCR testing (Standard of Care)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Catherine WexlerDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America.ORCID 0000-0003-1891-9165
May MalobaGlobal Health Innovations, Nairobi, Kenya.
Melinda BrownDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Natabhona MabachiDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Kathy GogginHealth Services and Outcomes Research, Children's Mercy Kansas City, Kansas City, MO, United States of America.
Brad GautneyGlobal Health Innovations, Dallas, TX, United States of America.
Beryne OdenyDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Sarah Finocchario-KesslerDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America.
University of Kansas Medical Center · USChildren's Mercy Hospital · USHealth Innovations (United States) · US

Funding

Piloting at-birth point of care HIV testing strategies in KenyaR01HD076673 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI KESSLER, SARAH FINOCCHARIO · 2013 to 2017
$3.4M
NICHD NIH HHS R01 HD076673
6 · The paper itself

Abstract

backgroundAt-birth and point-of-care (POC) HIV testing are emerging strategies to streamline infant HIV diagnosis and expedite ART initiation for HIV-positive infants. The purpose of this qualitative study was to evaluate factors influencing the provision and acceptance of at-birth POC testing among both HIV care providers and parents of HIV-exposed infants in Kenya.

methodsWe conducted semi-structured interviews with 26 HIV care providers and 35 parents of HIV-exposed infants (including 23 mothers, 6 fathers, and 3 mother-father pairs) at four study hospitals prior to POC implementation. An overview of best available evidence related to POC was presented to participants prior to each interview. Interviews probed about standard EID services, perceived benefits and risk of at-birth and POC testing, and suggested logistics of providing at-birth and POC. Interviews were audio recorded, translated (if necessary), and transcribed verbatim. Using the Transdisciplinary Model of Evidence Based Practice to guide analysis, transcripts were coded based on a priori themes related to environmental context, patient characteristics, and resources.

resultsMost providers (24/26) and parents (30/35) held favorable attitudes towards at-birth POC testing. The potential for earlier results to improve infant care and reduce parental anxiety drove preferences for at-birth POC testing. Parents with unfavorable views towards at-birth POC testing preferred standard testing at 6 weeks so that mothers could heal after birth and have time to bond with their newborn before-possibly-learning that their child was HIV-positive. Providers identified lack of resources (shortage of staff, expertise, and space) as a barrier. DISCUSSION: While overall acceptability of at-birth POC testing among HIV care providers and parents of HIV-exposed infants may facilitate uptake, barriers remain. Applying a task-shifting approach to implementation and ensuring providers receive training on at-birth POC testing may mitigate provider-related challenges. Comprehensive counseling throughout the antenatal and postpartum periods may mitigate patient-related challenges.

Indexed as

AdultAttitudeDecision MakingFemaleHealth PersonnelHIV InfectionsHumansInfant CareInfant, NewbornInterviews as TopicKenyaMaleParentsParturitionPoint-of-Care SystemsPregnancy

Identifiers

PMID31756242
PMCPMC6874324
OpenAlexW2990167892

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.