Evidence map›Paper›PMID 31756175›Full record

ArticleThe American journal of case reports2019

Starvation Ketoacidosis due to the Ketogenic Diet and Prolonged Fasting - A Possibly Dangerous Diet Trend.

Joanna C Blanco, Akshay Khatri, Alina Kifayat, Ronald Cho, Wilbert S Aronow

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05225467 (Development of Ketoacidosis During the Perioperative Period), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05225467 completednot on this mapstarted 2022, after this paper: background citation

Development of Ketoacidosis During the Perioperative Period: an Observational Study 'The DKAP Study'

Typeobservational_patient_registrySponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Ran2022 to 2023Enrolled58ConditionsKetosis, Keto Acidosis, Ketoses, Metabolic, Ketosis, Diabetic
3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. New insights into metabolism dysregulation after TBI.Journal of neuroinflammation · 2024
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. A Liraglutide Injection Superimposing a Starvation Acidosis: a Case Report.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joanna C BlancoDepartment of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Akshay KhatriDepartment of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Alina KifayatDepartment of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Ronald ChoDepartment of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Wilbert S AronowDepartment of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND The low-carbohydrate, high-fat ketogenic diet has been popularized in the press recently, touting multiple health benefits such as weight loss and increased energy. In this diet, participants intentionally push themselves into a state of ketosis and usually do not develop metabolic complications or illness unless put under certain circumstances such as stress and prolonged fasting. CASE REPORT We report a case of starvation ketoacidosis in a 60-year-old male with well-controlled diabetes mellitus type II following a strict ketogenic diet who then underwent prolonged fasting. CONCLUSIONS Although the ketogenic diet with or without periods of fasting might yield short-term weight loss, it has potentially dangerous side effects, including ketoacidosis. It is recommended that people, especially those with comorbidities such as diabetes mellitus type II, consult their physicians before initiating this diet. Clinicians must keep a broad differential when evaluating acute metabolic acidosis.

Indexed as

Diabetes Mellitus, Type 2Diet FadsDiet, KetogenicFastingHumansKetosisMaleMiddle AgedStarvationSyncope

Identifiers

PMID31756175
PMCPMC6883983

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.