Evidence map›Paper›PMID 31755865›Full record

ArticleeLife2019

Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto

Masahiro Oka, Sonoko Mura, Mayumi Otani, Yoichi Miyamoto, Jumpei Nogami, Kazumitsu Maehara, Akihito Harada, Taro Tachibana, Yoshihiro Yoneda, Yasuyuki Ohkawa

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 63 citations in OpenAlex.

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  12. Biomolecular condensates in immune cell fate.Nature reviews. Immunology · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Therapeutic targeting of exportin-1 beyond nuclear export.Trends in pharmacological sciences · 2025
    Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Masahiro OkaLaboratory of Nuclear Transport Dynamics, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, Japan.ORCID 0000-0003-0123-3060
Sonoko MuraBiomolecular Dynamics Group, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan.
Mayumi OtaniLaboratory of Nuclear Transport Dynamics, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, Japan.
Yoichi MiyamotoLaboratory of Nuclear Transport Dynamics, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, Japan.
Jumpei NogamiDepartment of Advanced Medical Initiatives, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Kazumitsu MaeharaDepartment of Advanced Medical Initiatives, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Akihito HaradaDepartment of Advanced Medical Initiatives, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Taro TachibanaDepartment of Bioengineering, Graduate School of Engineering, Osaka City University, Osaka, Japan.
Yoshihiro YonedaLaboratory of Biomedical Innovation, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan.
Yasuyuki OhkawaDepartment of Advanced Medical Initiatives, Faculty of Medicine, Kyushu University, Fukuoka, Japan.ORCID 0000-0001-6440-9954
Kyushu University · JPNational Institute of Biomedical Innovation, Health and Nutrition · JPOsaka City University · JPThe University of Osaka · JP

Funding

Japan Science and Technology Agency MJCR16G1Japan Society for the Promotion of Science 16H04789Japan Society for the Promotion of Science 16K14676Japan Society for the Promotion of Science 17H03608Japan Society for the Promotion of Science 17H03679Japan Society for the Promotion of Science 18H04802Japan Society for the Promotion of Science 18H05527Japan Society for the Promotion of Science 19H05244Japan Society for the Promotion of Science 25116008
6 · The paper itself

Abstract

We previously demonstrated that CRM1, a major nuclear export factor, accumulates at

Indexed as

Active Transport, Cell NucleusCell Line, TumorCell NucleusChromatinCytoplasmDNA-Binding ProteinsExportin 1 ProteinGene Expression Regulation, LeukemicHistone ChaperonesHomeodomain ProteinsHumansKaryopherinsLeukemia, Myeloid, AcuteMutationNuclear Export SignalsNuclear Pore Complex ProteinsChromatinDNA-Binding ProteinsExportin 1 ProteinHistone ChaperonesHomeodomain ProteinsKaryopherinsNPM1 protein, humanNuclear Export SignalsNuclear Pore Complex ProteinsNuclear ProteinsNucleophosminNUP214 protein, humanReceptors, Cytoplasmic and NuclearSET protein, humancell biologychromosomesCRM1gene expressionHOX clusterhumanleukemiaNPM1cnucleoporinSET-Nup214

Identifiers

PMID31755865
PMCPMC6874418
OpenAlexW2989618010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.