Evidence map›Paper›PMID 31755552›Full record

ArticleAllergy2020

IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids.

F Nicole Dijk, Susanne J Vijverberg, Natalia Hernandez-Pacheco, Katja Repnik, Leila Karimi, Marianna Mitratza, Niloufar Farzan, Martijn C Nawijn, Esteban G Burchard, Marjolein Engelkes and 6 more

Open access · bronzeAbstract readLetter
In one paragraph

Article in Allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Asthma Exacerbations: The Genes Behind the Scenes.Journal of investigational allergology & clinical immunology · 2023
    Review
  4. Observational
  5. Review
  6. Review
  7. Article
  8. Review
  9. Pharmacogenetics of Pediatric Asthma: Current Perspectives.Pharmacogenomics and personalized medicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 4 countries.

F Nicole DijkDepartment of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-7680-4951
Susanne J VijverbergDepartment of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-4579-4081
Natalia Hernandez-PachecoResearch Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.ORCID 0000-0002-6313-1847
Katja RepnikCenter for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Leila KarimiDepartment of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Marianna MitratzaDivision of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Niloufar FarzanDepartment of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Martijn C NawijnLaboratory of Allergology and Pulmonary Diseases, Pathology and Medical Biology, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Esteban G BurchardDepartment of Medicine, University of California, San Francisco, CA, USA.
Marjolein EngelkesDepartment of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Katia M VerhammeDepartment of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Uroš PotočnikCenter for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Maria Pino-YanesResearch Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.ORCID 0000-0003-0332-437X
Dirkje S PostmaDepartment of Pulmonary Diseases, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Anke-Hilse Maitland-van der ZeeDepartment of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-0414-3442
Gerard H KoppelmanDepartment of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-8567-3252
University Medical Center Groningen · NLUtrecht University · NLErasmus MC · NLUniversidad de La Laguna · ESUniversity of Maribor · SIUniversity of California, San Francisco · US

Funding

The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with AsthmaR01HL117004 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, SEIBOLD, MAX A · 2013 to 2022
$9.3M
Social Interventions to address disparities In young adult tobacco useP60MD006902 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN · 2012 to 2016
$6.4M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
Transcriptomic and Pharmacogenetic Asthma Endotypes in Minority ChildrenR01HL135156 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A, ZIV, ELAD · 2017 to 2021
$4.1M
Genes, air pollution, and asthma severity in minority childrenR01MD010443 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEIBOLD, MAX A, ZIV, ELAD · 2016 to 2020
$3.8M
Genetic Control of Airway Epithelium Gene Expression in Childhood AsthmaticsR01HL128439 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A · 2015 to 2019
$3.1M
Gene-Environment Analyses of Early Life Exposures and Asthma in Ethnically Diverse ChildrenR21ES024844 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ, GAUDERMAN, WILLIAM JAMES · 2015 to 2017
$509k
LEARNED MODIFICATION OF VISCERAL FUNCTION IN MANZ01AG000067 · NIA · AGING · PI ENGEL, B T · 1985 to 1988
–
NHLBI NIH HHS R01 HL117004NHLBI NIH HHS R01 HL128439NHLBI NIH HHS R01 HL135156NIEHS NIH HHS R01 ES015794NIEHS NIH HHS R21 ES024844NIMHD NIH HHS P60 MD006902NIMHD NIH HHS R01 MD010443
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Asthmatic AgentsAsthmaDisease ProgressionAdministration, InhalationAdolescentAdrenal Cortex HormonesChildHumansInterleukin-1 Receptor-Like 1 ProteinAdrenal Cortex HormonesAnti-Asthmatic AgentsIL1RL1 protein, humanInterleukin-1 Receptor-Like 1 Protein

Identifiers

PMID31755552
PMCPMC7176513
OpenAlexW2991634910

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.