ArticleCNS neuroscience & therapeutics2020
Assessment of three essential tremor genetic loci in sporadic Parkinson's disease in Eastern China.
Article in CNS neuroscience & therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Association Analysis of Essential Tremor-Associated Genetic Variants in Sporadic Late-Onset Parkinson's Disease.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024Article
- Association analysis of SYT11, FGF20, GCH1 rare variants in Parkinson's disease.CNS neuroscience & therapeutics · 2022Article
- Assessment of three essential tremor genetic loci in sporadic Parkinson's disease in Eastern China.CNS neuroscience & therapeutics · 2020Article
- Association of the Plasma Long Non-coding RNAFrontiers in neurology · 2020Article
- Parkinson's Disease in Teneurin Transmembrane Protein 4 (Frontiers in genetics · 2020Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to investigate potential genetic overlap between essential tremor and Parkinson's disease in a cohort of 825 subjects from an Eastern Chinese population.
methodsA total of 441 Parkinson's disease patients and 384 healthy controls were recruited. The MassARRAY System was used to detect three essential tremor-related single nucleotide polymorphisms. Odds ratio (OR) and 95% confidential interval (CI) were calculated to assess the relationship between polymorphisms and Parkinson's disease susceptibility.
resultsOur results demonstrated that the odds ratios of rs3794087 of SLC1A2, rs9652490 of LINGO1, and rs17590046 of PPARGC1A were 0.71 (95% CI = 0.55-0.91), 0.99 (95% CI = 0.78-1.26), and 0.88 (95% CI = 0.62-1.25), respectively.
conclusionAn essential tremor SNP (rs3794087 of SLC1A2) is associated with a decreased risk of PD in the Eastern Han Chinese population, while rs9652490 (LINGO1) and rs17590046 (PPARGC1A) do not show an association.
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