ArticleOrthopaedic surgery2019
Epidemiological Characteristics of 1196 Patients with Spinal Metastases: A Retrospective Study.
Article in Orthopaedic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quality of life in patients with malignant spinal cord compression: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Epidemiology and neurological profiling of vertebral tumors in Mexico: a five-year review from a tertiary referral center.Spinal cord series and cases · 2026Observational
- Feasibility of Using Short-Segment Instrumentation and Vertebral Body Reconstruction for the Treatment of Metastatic Disease in the Thoracic Spine.Journal of clinical medicine · 2026Article
- Tumor-specific outcomes in spinal metastases: a systematic review and meta-analysis.Journal of spine surgery (Hong Kong) · 2026Article
- The Prognostic Impact of the Ki-67 Proliferation Index in Patients with Surgically Treated Spinal Metastases.Cancers · 2026Article
- Article
- Epidemiology and surgical management of the lower lumbar spinal metastases in China: a multicenter retrospective study.Scientific reports · 2025Article
- A critical appraisal of clinical guidelines on radiotherapy treatments for spinal metastasis.Neurosurgical review · 2025Review
- Effect of percutaneous kyphoplasty combined with percutaneous microwave ablation on pain and clinical outcome in patients with spinal metastases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- The Classification of Metastatic Spine Cancer and Spinal Compression Fractures by Using CNN and SVM Techniques.Bioengineering (Basel, Switzerland) · 2024Article
- Dynamic contrast-enhanced magnetic resonance imaging parameter changes as an early biomarker of tumor responses following radiation therapy in patients with spinal metastases: a systematic review.Radiation oncology journal · 2023Article
- [Spinal metastases combined with leptomeningeal metastasis: A case report].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Prediction of Primary Tumor Sites in Spinal Metastases Using a ResNet-50 Convolutional Neural Network Based on MRI.Cancers · 2023Article
- The outcome of spine metastatic after surgery: a case series.Annals of medicine and surgery (2012) · 2023Article
- Clinical Outcome and Histological Findings After Induced Leakage of PMMA Loaded With Methotrexate and Cisplatin During Vertebroplasty: Experimental Model in Pigs.Global spine journal · 2023Article
- Complication Avoidance in Surgical Management of Vertebral Column Tumors.Current oncology (Toronto, Ont.) · 2022Review
- Multidisciplinary Approach to Patients With Metastatic Spinal Cord Compression: A Diagnostic Therapeutic Algorithm to Improve the Neurological Outcome.Frontiers in oncology · 2022Article
- An Overview of Decision Making in the Management of Metastatic Spinal Tumors.Indian journal of orthopaedics · 2021Review
- Interventional and Non-interventional Medical Rehabilitation Approaches to Axial Spine Pain in Vertebral Metastatic Disease.Frontiers in pain research (Lausanne, Switzerland) · 2021Review
- Epidemiology of spinal cord and column tumors.Neuro-oncology practice · 2020Article
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8 authors.
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Abstract
objectivesTo describe the epidemiological characteristics of patients with spinal metastases between 2007 and 2019.
methodsPatients with spinal metastases were identified from several clinical centers in China between January 2007 and July 2019. Demographics, primary tumor types, spinal involvement, and Clinical indicators of each patient were reviewed.
resultsA total of 1196 patients were included in this study, 717 males (59.95%) and 479 females (40.05%), with a male to female ratio of 1.50:1. Most patients (63.71%) were in the ages range of 50 to 69 years. The mean age was 58.6 ± 11.6 (range 13-89) years and the median age was 59.0 years. The average age of females was younger than that of males, and the difference was statistically significant. The proportion of male patients over 60 years old was higher than that of females, and the difference was statistically significant. The most common primary tumor was lung cancer (n = 437, 36.54%), followed by unknown origin (n = 194, 16.22%), kidney cancer (n = 78, 6.52%), breast cancer (n = 76, 6.35%), and liver/biliary cancer (n = 75, 6.27%). The most common primary tumor was lung cancer in both males and females, followed by unknown origin in males and breast cancer in females. There were 730 patients (61.04%) in the subgroup of the number<3; the highest level was lumbar vertebrae, with 250 patients (34.25%). The remaining 466 patients (38.96%) were included in the subgroup of the number ≥ 3; the highest level was tumor metastasis of multiple-level of spine, with 334 patients (71.67%). Among the 1196 patients, spinal cord injury occurred in 54.01% of patients, 76.34% of patients developed moderate and above pain, 55.69% of patients had metastatic spinal cord compression, and only 26.67% of patients had a clear history of primary tumors.
conclusionThis study provided a relatively detailed description of epidemiological characteristics in spinal metastases in China, which could assist orthopaedic surgeons to understand the clinical characteristics of spinal metastases, and is of great significance in guiding clinical diagnoses and scientific research.
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