Evidence map›Paper›PMID 31755176›Full record

ArticleAging cell2020

Nociceptive transient receptor potential canonical 7 (TRPC7) mediates aging-associated tumorigenesis induced by ultraviolet B.

Wen-Li Hsu, Ming-Hsien Tsai, Ching-Ying Wu, Jui-Lin Liang, Jian-He Lu, Jennifer S Kahle, Hsin-Su Yu, Chia-Jung Yen, Chen-Tung Yen, Yi-Chun Hsieh and 5 more

Open access · goldAbstract read
In one paragraph

Article in Aging cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation.International journal of molecular sciences · 2022
    Article
  8. Article
  9. Mechanisms of Broad-Band UVB Irradiation‒Induced Itch in Mice.The Journal of investigative dermatology · 2021
    Article
  10. Review
  11. A novel strategy for treating cancer: understanding the role of CaExploration of targeted anti-tumor therapy · 2021
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Wen-Li HsuResearch Organization for Nano & Life Innovation, Waseda University, Shinjuku, Tokyo, Japan.ORCID 0000-0003-1034-4977
Ming-Hsien TsaiEmerging Compounds Research Center, General Research Service Center, National Pingtung University of Science and Technology, Pingtung, Taiwan.
Ching-Ying WuDepartment of Dermatology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Jui-Lin LiangDepartment of General Surgery, Chi-Mei Medical Center, Liouying, Tainan, Taiwan.
Jian-He LuGraduate Institute of Medicine, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Jennifer S KahleDepartment of Psychological Sciences, University of San Diego, San Diego, CA, USA.
Hsin-Su YuDepartment of Dermatology, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chia-Jung YenRegenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chen-Tung YenDepartment of Life Science, National Taiwan University, Taipei, Taiwan.
Yi-Chun HsiehEmerging Compounds Research Center, General Research Service Center, National Pingtung University of Science and Technology, Pingtung, Taiwan.
Yung-Yun HuangSchool of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Li-Ching LinSchool of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Tsung-Fu TsaiSchool of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chu-Huang ChenGraduate Institute of Medicine, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.ORCID 0000-0002-1509-7883
Tohru YoshiokaRegenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.ORCID 0000-0003-2831-6421
Kaohsiung Medical University · TWNational Pingtung University of Science and Technology · TWAlliant International University · USChi Mei Medical Center · TWWaseda University · JP

Funding

MECHANISM FOR PRESSURE COLLAPSE WITHOUT FIBRILLATIONR01HL064050 · NHLBI · UNIVERSITY OF MEMPHIS · PI MALKIN, ROBERT A · 2000 to 2002
$636k
Aim for the Top Universities Grant KMUH107-7R66Aim for the Top Universities Grant KMU-TP104D04Aim for the Top Universities Grant KMU-TP105D02Aim for the Top Universities Grant TP104D00Aim for the Top Universities Grant TP104D01Aim for the Top Universities Grant TP104D22Aim for the Top Universities Grant TP105D00Aim for the Top Universities Grant TP105D01Aim for the Top Universities Grant TP105D15Aim for the Top Universities Grant TP105G02Chi Mei Medical Center CLFHR10509Chi Mei Medical Center CLFHR10709Ministry of Science and Technology, Taiwan 105-2628-B-037-006-MY3Ministry of Science and Technology, Taiwan MOST104-2314-B-037-060Ministry of Science and Technology, Taiwan MOST106-2314-B-037-069Ministry of Science and Technology, Taiwan MOST106-2321-B-037-003Ministry of Science and Technology, Taiwan MOST107-2321-B-037-002School Cooperation Grant DK106001School Cooperation Grant DK107002Texas Heart Institute #765-64050University of Cologne-Kaohsiung Medical University Agency SH000151
6 · The paper itself

Abstract

Aging, cancer, and longevity have been linked to intracellular Ca

Indexed as

AnimalsCarcinogenesisHumansKeratinocytesMiceMice, KnockoutSkin AgingTRPC Cation ChannelsUltraviolet RaysTRPC7 protein, humanTrpc7 protein, mouseTRPC Cation Channelsagingp53TRPC7tumorigenesistumor initiator geneultraviolet pathology

Identifiers

PMID31755176
PMCPMC6974716
OpenAlexW2989604367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.