Evidence map›Paper›PMID 31755171›Full record

ArticleBipolar disorders2021

Quantification of brain proton longitudinal relaxation (T

Joe Necus, Fiona Elizabeth Smith, Peter Edward Thelwall, Carly Jay Flowers, Nishant Sinha, Peter Neal Taylor, Andrew Matthew Blamire, Yujiang Wang, David Andrew Cousins

Abstract read
In one paragraph

Article in Bipolar disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joe NecusTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0003-0832-3130
Fiona Elizabeth SmithTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Peter Edward ThelwallTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0003-1795-6394
Carly Jay FlowersTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Nishant SinhaTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Peter Neal TaylorTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Andrew Matthew BlamireTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Yujiang WangTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
David Andrew CousinsTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.

Funding

Medical Research Council BH135495Medical Research Council MR/L006642/1Wellcome TrustWellcome Trust 208940/Z/17/ZWellcome Trust 210109/Z/18/Z
6 · The paper itself

Abstract

backgroundProton longitudinal relaxation (T

methodsEuthymic patients with bipolar disorder receiving lithium (n = 18, BDL) and those on other medications but naïve to lithium (n = 20, BDC) underwent quantitative T

resultsNo significant differences in T

conclusionsThe higher T

Indexed as

Bipolar DisorderLithiumBrainHumansLithium CompoundsMagnetic Resonance ImagingProtonsLithiumLithium CompoundsProtonsbipolar disorderlithiumquantitative MRIT1 relaxometry

Identifiers

PMID31755171
PMCPMC7891392

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.