Evidence map›Paper›PMID 31755098›Full record

ArticleEuropean journal of immunology2020

CD28 and CD57 define four populations with distinct phenotypic properties within human CD8

Luca Pangrazzi, Jürgen Reidla, José Antonio Carmona Arana, Erin Naismith, Carina Miggitsch, Andreas Meryk, Michael Keller, Adelheid Alma Nora Krause, Franz Leonard Melzer, Klemens Trieb and 3 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 68 citations in OpenAlex.

  1. Trial
  2. CD8Leukemia · 2024
    Trial
  3. Sustained immunotolerance in multiple sclerosis after stem cell transplant.Annals of clinical and translational neurology · 2022
    Trial
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. The Presence of Non-Exhausted Senescent T Cells in Breast Cancer Patients.Asian Pacific journal of cancer prevention : APJCP · 2025
    Article
  15. Polyfunctional CD8Molecular oncology · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Luca PangrazziDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.ORCID 0000-0003-0673-4577
Jürgen ReidlaDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
José Antonio Carmona AranaDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
Erin NaismithDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
Carina MiggitschDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
Andreas MerykDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
Michael KellerDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
Adelheid Alma Nora KrauseDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
Franz Leonard MelzerDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
Klemens TriebDepartment of Orthopedic Surgery, Hospital Wels-Grieskirchen, Grieskirchnerstrasse 42, Wels, Austria.
Michael SchirmerDepartment of Internal Medicine, Clinic II, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Beatrix Grubeck-LoebensteinDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
Birgit WeinbergerDepartment of Immunology, Institute for Biomedical Aging Research, University of Innsbruck, Rennweg 10, Innsbruck, Austria.
Universität Innsbruck · ATInnsbruck Medical University · ATKlinikum Wels-Grieskirchen · AT

Funding

Austrian Science Fund Doctoral programme HOROSAustrian Science Fund W1253Austrian Science Fund FWF W 1253EU H2020 633964European Union Seventh Framework Programme 280873
6 · The paper itself

Abstract

After repeated antigen exposure, both memory and terminally differentiated cells can be generated within CD8

Indexed as

CD28 AntigensCD57 AntigensCD8-Positive T-LymphocytesHumansPhenotypeT-Lymphocyte SubsetsCD28 AntigensCD57 AntigensCD28CD57CD8+ T cellscell differentiationvaccination

Identifiers

PMID31755098
PMCPMC7079235
OpenAlexW2990280879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.