Evidence map›Paper›PMID 31754997›Full record

ReviewMolecular neurobiology2020

The Role of Xenobiotics and Trace Metals in Parkinson's Disease.

Geir Bjørklund, Maryam Dadar, Salvatore Chirumbolo, Jan Aaseth

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. A new metabolic model ofLife science alliance · 2023
    Article
  6. Article
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Geir BjørklundCouncil for Nutritional and Environmental Medicine (CONEM), Toften 24, 8610, Mo i Rana, Norway. bjorklund@conem.org.ORCID http://orcid.org/0000-0003-2632-3935
Maryam DadarRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
Salvatore ChirumboloDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Jan AasethResearch Department, Innlandet Hospital Trust, Brumunddal, Norway.
Razi Vaccine and Serum Research Institute · IRSechenov University · RUThe Research Council of Norway · NOUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on the etiopathogenesis of Parkinson's disease (PD) has in the very recent years earned many insightful cues about the involvement of xenobiotics and metal pollutants in the onset and exacerbation of this neurodegenerative disorder. Furthermore, particularly for metal pollutants, the hypothesis about the role exerted by impaired mitochondrial function is gaining a leading causative role. In this review, we outline the role of environmental pollution in the pathogenesis of PD, as the prolonged exposure to xenobiotics may account for the majority of PD reported cases, expanding the debate also about some suggested therapeutic approaches.

Indexed as

AnimalsDopaminergic NeuronsHumansMetalsMitochondriaParkinson DiseaseSubstantia NigraXenobioticsMetalsXenobioticsAlpha-synucleinChelating agentsDopamineIronManganeseOxidative stressSubstantia nigra

Identifiers

PMID31754997
OpenAlexW2990896574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.