Evidence map›Paper›PMID 31754908›Full record

ArticleLasers in medical science2020

Photobiomodulation reduces cell death and cytokine production in C2C12 cells exposed to Bothrops venoms.

Viviane Almeida Gouveia, Flavia Regina Ferreira Soares Pisete, Cristiane Luize Rocha Wagner, Maria Aparecida Dalboni, Ana Paula Ligeiro de Oliveira, José Carlos Cogo, Stella Regina Zamuner

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Exploring the ability of low-level laser irradiation to reduce myonecrosis and increase Myogenin transcription after Bothrops jararacussu envenomation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Viviane Almeida GouveiaPostgraduate Program in Medicine, Universidade Nove de Julho - UNINOVE, R: Vergueiro, 235 - Bairro Liberdade, São Paulo, SP, 01504-000, Brazil.
Flavia Regina Ferreira Soares PisetePostgraduate Program in Medicine, Universidade Nove de Julho - UNINOVE, R: Vergueiro, 235 - Bairro Liberdade, São Paulo, SP, 01504-000, Brazil.
Cristiane Luize Rocha WagnerPostgraduate Program in Medicine, Universidade Nove de Julho - UNINOVE, R: Vergueiro, 235 - Bairro Liberdade, São Paulo, SP, 01504-000, Brazil.
Maria Aparecida DalboniPostgraduate Program in Medicine, Universidade Nove de Julho - UNINOVE, R: Vergueiro, 235 - Bairro Liberdade, São Paulo, SP, 01504-000, Brazil.
Ana Paula Ligeiro de OliveiraPostgraduate Program in Biofotonic, Universidade Nove de Julho - UNINOVE, R: Vergueiro, 235 - Liberdade, São Paulo, SP, Brazil.
José Carlos CogoPostgraduate Program in Bioengenharia, Instituto Científico e Tecnológico - Universidade Brasil, Itaquera, São Paulo, SP, Brazil.
Stella Regina ZamunerPostgraduate Program in Medicine, Universidade Nove de Julho - UNINOVE, R: Vergueiro, 235 - Bairro Liberdade, São Paulo, SP, 01504-000, Brazil. stella.rz@uni9.pro.br.ORCID http://orcid.org/0000-0002-4694-7617
Universidade Nove de Julho · BRUniversidade Brasil · BR

Funding

FAPESP 2017/13503-1
6 · The paper itself

Abstract

Snakebites caused by the genus Bothrops are often associated with severe and complex local manifestations such as edema, pain, hemorrhage, and myonecrosis. Conventional treatment minimizes the systemic effects of venom; however, their local action is not neutralized. The purpose of this study was to evaluate the effect of photobiomodulation (PBM) on C2C12 muscle cells exposed to B. jararaca, B. jararacussu, and B. moojeni venoms on events involved in cell death and the release of inflammatory mediators. Cells were exposed to venoms and immediately irradiated with low-level laser (LLL) application in continuous wave at the wavelength of 660 nm, energy density of 4.4 J/cm

Indexed as

Low-Level Light TherapyAnimalsApoptosisBothropsCell LineCell ShapeCrotalid VenomsCytokinesMiceMuscle CellsCrotalid VenomsCytokinesApoptosisB. jararacaB. jararacussuB. moojeniMuscle cellsNecrosis photobiomodulation

Identifiers

PMID31754908
OpenAlexW2990502975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.